DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Papss and MET14

DIOPT Version :9

Sequence 1:	NP_730460.1	Gene:	Papss / 40167	FlyBaseID:	FBgn0020389	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	NP_012925.3	Gene:	MET14 / 853869	SGDID:	S000001484	Length:	202	Species:	Saccharomyces cerevisiae

Alignment Length:	207	Identity:	112/207 - (54%)
Similarity:	141/207 - (68%)	Gaps:	5/207 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 VATNVTEQKHHVTRETRGKNLGLCRGFRGCTVWLTGLSGAGKTSIAFELEAYLVSRGIPAYGLDG 110
            :|||:|...:....|.:.     .|...|||:||||||.:||::||..||..|:.:.:.||.|||
Yeast     1 MATNITWHPNLTYDERKA-----LRKQDGCTIWLTGLSASGKSTIACALEQLLLQKNLSAYRLDG 60

  Fly   111 DNIRTGLNKNLGFTPADREENIRRVGEVAKLFADSGVVAICSFVSPFADDREMARKIHKDAGLKF 175
            ||||.||||:|||:..||.|||||:.||:||||||..::|.||:||:..||:.||::||:|||||
Yeast    61 DNIRFGLNKDLGFSEKDRNENIRRISEVSKLFADSCAISITSFISPYRVDRDRARELHKEAGLKF 125

  Fly   176 YEIFVDTPLDVCETRDVKGLYKKAREGVIKGFTGITQEYERPQMPELVVNTHGYTVRESTQKLVT 240
            .|||||.||:|.|.||.|||||||||||||.||||:..||.|:.|||.:.|...||.|....:..
Yeast   126 IEIFVDVPLEVAEQRDPKGLYKKAREGVIKEFTGISAPYEAPKAPELHLRTDQKTVEECATIIYE 190

  Fly   241 LLEQEGIIPRSL 252
            .|..|.||.:.|
Yeast   191 YLISEKIIRKHL 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Papss	NP_730460.1	APS_kinase	73..228	CDD:279865	98/154 (64%)
		sopT	270..648	CDD:273023
		ATPS	279..650	CDD:173895
MET14	NP_012925.3	apsK	7..192	CDD:129547	103/189 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345344
Domainoid	1	1.000	203	1.000	Domainoid score	I545
eggNOG	1	0.900	-	-		E1_COG0529
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H81740
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S866
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000913
OrthoInspector	1	1.000	-	-		oto99990
orthoMCL	1	0.900	-	-		OOG6_100343
Panther	1	1.100	-	-	LDO	PTHR11055
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R633
SonicParanoid	1	1.000	-	-		X525
TreeFam	0	0.000	Not matched by this tool.
	12	11.720