DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Papss and APS2

DIOPT Version :9

Sequence 1:	NP_730460.1	Gene:	Papss / 40167	FlyBaseID:	FBgn0020389	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	NP_564099.1	Gene:	APS2 / 838580	AraportID:	AT1G19920	Length:	476	Species:	Arabidopsis thaliana

Alignment Length:	462	Identity:	236/462 - (51%)
Similarity:	314/462 - (67%)	Gaps:	22/462 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   210 ITQEYERPQMPELVVNTHGYTVRESTQKLVTLLEQEGI---------IPRSLRDVD---LLPELY 262
            ||....|...|....|...:....:....:.|:.:..:         :..||.|.|   |:..:.
plant    13 ITLFQPRNSKPSSFTNQISFLSSSNNNPFLNLVYKRNLTMQSVSKMTVKSSLIDPDGGELVELIV 77

  Fly   263 PSESIATEALRHEAESLQAIEISTVELQWVQVLAEGWAYPLRGFMREDEYLQTLHFNTLQSGMDG 327
            |...|..:  :.|:|::..::::.::|:||.|::||||.||:||||||||||:||||:|:. .:|
plant    78 PETEIGVK--KAESETMPKVKLNQIDLEWVHVISEGWASPLKGFMREDEYLQSLHFNSLRL-KNG 139

  Fly   328 SYRENHSVPIVLSATQADKDRLDGCSSLTLKY-QGKAVAILRRPEFYFQRKEERLARQFGTSNPN 391
            :: .|.|:||||:.....|:::....::.|.. ||..:..||..|.|...||||:||.:||::|.
plant   140 TF-VNMSLPIVLAIDDDTKEQIGSSENVALVCPQGDIIGSLRSVEIYKHNKEERIARTWGTTSPG 203

  Fly   392 HPYSKQ-VYESGDYLVGGDLAVIERIRWEDGLDQYRLTPNELRRRFKELNADAIFAFQLRNPIHN 455
            .||.:: :..||::|:||||.|.|.|::.||||.|||:|.:||..|....|||:||||||||:||
plant   204 LPYVEEYITPSGNWLIGGDLEVFEPIKYNDGLDHYRLSPKQLREEFDNRQADAVFAFQLRNPVHN 268

  Fly   456 GHALLMQDTRRQLLERGFKQPVLLLHPLGGWTKDDDVPLDVRMKQHQAVLDAGVLRREDTVLAIF 520
            ||||||.|||::|||.|:|.||||||||||:||.|||||||||:||..||:.|||..:.|:::||
plant   269 GHALLMNDTRKRLLEMGYKNPVLLLHPLGGFTKADDVPLDVRMEQHSKVLEDGVLDPKTTIVSIF 333

  Fly   521 PSPMMYAGPTEVQWHAKARMNAGANFYIVGRDPAGMPHPAKETYPDGNLYDATHGARVLKMAQGL 585
            ||||.||||||||||||||:||||||||||||||||.||.::.    :|||..||.|||.||.||
plant   334 PSPMHYAGPTEVQWHAKARINAGANFYIVGRDPAGMGHPTEKR----DLYDPDHGKRVLSMAPGL 394

  Fly   586 DSMEILPFRVAAYDKSASRMAFFEPKRKDEFEFISGTKMRTLAKTGASPPDGFMEPEAWRILATY 650
            :.:.||||||||||....:||||:|.|..||.|||||||||.|:||.:||||||.|..|.:|..|
plant   395 EKLNILPFRVAAYDTIEKKMAFFDPSRAKEFLFISGTKMRTYARTGENPPDGFMCPSGWNVLVKY 459

  Fly   651 YQNLPQS 657
            |::|.:|
plant   460 YESLQES 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Papss	NP_730460.1	APS_kinase	73..228	CDD:279865	5/17 (29%)
		sopT	270..648	CDD:273023	218/379 (58%)
		ATPS	279..650	CDD:173895	217/372 (58%)
APS2	NP_564099.1	sopT	67..458	CDD:273023	223/398 (56%)
APS2	NP_564099.1	ATPS	92..459	CDD:173895	217/372 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	322	1.000	Domainoid score	I273
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	460	1.000	Inparanoid score	I369
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D528280at2759
OrthoFinder	1	1.000	-	-		FOG0000913
OrthoInspector	1	1.000	-	-		otm3262
orthoMCL	1	0.900	-	-		OOG6_100343
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X525
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.920