DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Papss and APS4

DIOPT Version :9

Sequence 1:	NP_730460.1	Gene:	Papss / 40167	FlyBaseID:	FBgn0020389	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	NP_199191.1	Gene:	APS4 / 834400	AraportID:	AT5G43780	Length:	469	Species:	Arabidopsis thaliana

Alignment Length:	440	Identity:	234/440 - (53%)
Similarity:	309/440 - (70%)	Gaps:	37/440 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   224 VNTHGYTVRESTQKLVTLLEQEG------IIPRSLRDVDLLPELYPSESIATEALRHEAESLQA- 281
            |:..|.:|:..      |:|.:|      ::..|.|.|                ::||||::.|
plant    42 VSRRGLSVKSG------LIEPDGGKLMNLVVEESRRRV----------------MKHEAETVPAR 84

  Fly   282 IEISTVELQWVQVLAEGWAYPLRGFMREDEYLQTLHFNTLQSGMDGSYRENHSVPIVLSATQADK 346
            |:::.|:|:||.||:||||.||:||||:.|:|||||||:.:. .|||. .|.||||||:.....|
plant    85 IKLNRVDLEWVHVLSEGWASPLKGFMRQSEFLQTLHFNSFRL-EDGSV-VNMSVPIVLAIDDDQK 147

  Fly   347 DRLDGCSSLTL-KYQGKAVAILRRPEFYFQRKEERLARQFGTSNPNHPYSKQ-VYESGDYLVGGD 409
            .|:...:.:|| ...|..:|||...|.|...||||:||.:||:....||::: :.::|::|:|||
plant   148 FRIGDSNQVTLVDSVGNPIAILNDIEIYKHPKEERIARTWGTTARGLPYAEEAITKAGNWLIGGD 212

  Fly   410 LAVIERIRWEDGLDQYRLTPNELRRRFKELNADAIFAFQLRNPIHNGHALLMQDTRRQLLERGFK 474
            |.|:|.|::.||||::||:|::||..|....|||:||||||||:||||||||.||||:|||.|:|
plant   213 LQVLEPIKYNDGLDRFRLSPSQLREEFIRRGADAVFAFQLRNPVHNGHALLMTDTRRRLLEMGYK 277

  Fly   475 QPVLLLHPLGGWTKDDDVPLDVRMKQHQAVLDAGVLRREDTVLAIFPSPMMYAGPTEVQWHAKAR 539
            .|||||:||||:||.|||||..||:||:.||:.|||..|.||::||||||:||||||||||||||
plant   278 NPVLLLNPLGGFTKADDVPLSWRMRQHEKVLEDGVLDPETTVVSIFPSPMLYAGPTEVQWHAKAR 342

  Fly   540 MNAGANFYIVGRDPAGMPHPAKETYPDGNLYDATHGARVLKMAQGLDSMEILPFRVAAYDKSASR 604
            :||||||||||||||||.||.::.    :||||.||.:||.||.||:.:.||||:||||||:..:
plant   343 INAGANFYIVGRDPAGMGHPTEKR----DLYDADHGKKVLSMAPGLERLNILPFKVAAYDKTQGK 403

  Fly   605 MAFFEPKRKDEFEFISGTKMRTLAKTGASPPDGFMEPEAWRILATYYQNL 654
            ||||:|.|..:|.||||||||.|||...:||||||.|..|::|..||.:|
plant   404 MAFFDPSRSQDFLFISGTKMRGLAKKKENPPDGFMCPSGWKVLVDYYDSL 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Papss	NP_730460.1	APS_kinase	73..228	CDD:279865	1/3 (33%)
		sopT	270..648	CDD:273023	221/380 (58%)
		ATPS	279..650	CDD:173895	218/373 (58%)
APS4	NP_199191.1	sopT	56..448	CDD:273023	226/413 (55%)
APS4	NP_199191.1	ATPS	84..449	CDD:173895	217/370 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	322	1.000	Domainoid score	I273
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	460	1.000	Inparanoid score	I369
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D528280at2759
OrthoFinder	1	1.000	-	-		FOG0000913
OrthoInspector	1	1.000	-	-		otm3262
orthoMCL	1	0.900	-	-		OOG6_100343
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X525
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.830