DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Papss and AKN2

DIOPT Version :9

Sequence 1:	NP_730460.1	Gene:	Papss / 40167	FlyBaseID:	FBgn0020389	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	NP_195704.1	Gene:	AKN2 / 830153	AraportID:	AT4G39940	Length:	293	Species:	Arabidopsis thaliana

Alignment Length:	260	Identity:	104/260 - (40%)
Similarity:	139/260 - (53%)	Gaps:	48/260 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 LPSVEKPEDACLQV----------ATNVTEQ----------KHHVTRETRGKNLG---------- 67
            ||:...|.|:...|          |.||:.|          ...:.:|  |:|.|
plant    36 LPASSIPADSRKLVANSTSFHPISAVNVSAQASLTADFPALSETILKE--GRNNGKEKAENIVWH 98

  Fly    68 ---LCRGFR-------GCTVWLTGLSGAGKTSIAFELEAYLVSRGIPAYGLDGDNIRTGLNKNLG 122
               :||..|       ||.||:|||||:||:::|..|...|..||...|.|||||:|.|||::|.
plant    99 ESSICRCDRQQLLQQKGCVVWITGLSGSGKSTVACALSKALFERGKLTYTLDGDNVRHGLNRDLT 163

  Fly   123 FTPADREENIRRVGEVAKLFADSGVVAICSFVSPFADDREMARKIHKDAGLKFYEIFVDTPLDVC 187
            |....|.|||||:|||||||||.||:.|.|.:||:..||:..|.:..|.  .|.|:|:|.||.||
plant   164 FKAEHRTENIRRIGEVAKLFADVGVICIASLISPYRRDRDACRSLLPDG--DFVEVFMDVPLHVC 226

  Fly   188 ETRDVKGLYKKAREGVIKGFTGITQEYERPQMPELVVNTHG----YTVRESTQKLVTLLEQEGII 248
            |:||.|||||.||.|.|||||||...||.|...|:|:...|    .:.|:..:.:::.|:.:|.:
plant   227 ESRDPKGLYKLARAGKIKGFTGIDDPYEAPVNCEVVLKHTGDDESCSPRQMAENIISYLQNKGYL 291

Fly 249 248
plant 292 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Papss	NP_730460.1	APS_kinase	73..228	CDD:279865	85/161 (53%)
		sopT	270..648	CDD:273023
		ATPS	279..650	CDD:173895
AKN2	NP_195704.1	CysC	93..293	CDD:223603	91/201 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	168	1.000	Domainoid score	I1175
eggNOG	1	0.900	-	-		E1_COG0529
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000913
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100343
Panther	1	1.100	-	-	O	PTHR11055
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X525
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.810