DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Papss and APS1

DIOPT Version :9

Sequence 1:	NP_730460.1	Gene:	Papss / 40167	FlyBaseID:	FBgn0020389	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	NP_188929.1	Gene:	APS1 / 821861	AraportID:	AT3G22890	Length:	463	Species:	Arabidopsis thaliana

Alignment Length:	399	Identity:	235/399 - (58%)
Similarity:	295/399 - (73%)	Gaps:	9/399 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   258 LPELYPSESIATEALRHEAESLQAIEISTVELQWVQVLAEGWAYPLRGFMREDEYLQTLHFNTLQ 322
            |.||...|....|. :|||..|..:|::.::|||:.||:||||.||.|||||.|:|||||||:|:
plant    58 LVELIVEEPKRREK-KHEAADLPRVELTAIDLQWMHVLSEGWASPLGGFMRESEFLQTLHFNSLR 121

  Fly   323 SGMDGSYRENHSVPIVLSATQADKDRLDGCSSLTL-KYQGKAVAILRRPEFYFQRKEERLARQFG 386
            .. |||. .|.||||||:.....|.|:...:.:.| ...|..||||...|.|...||||:||.:|
plant   122 LD-DGSV-VNMSVPIVLAIDDEQKARIGESTRVALFNSDGNPVAILSDIEIYKHPKEERIARTWG 184

  Fly   387 TSNPNHPY-SKQVYESGDYLVGGDLAVIERIRWEDGLDQYRLTPNELRRRFKELNADAIFAFQLR 450
            |:.|..|| .:.:..:|::|:||||.|:|.:::.||||::||:|.|||:..::.||||:||||||
plant   185 TTAPGLPYVDEAITNAGNWLIGGDLEVLEPVKYNDGLDRFRLSPAELRKELEKRNADAVFAFQLR 249

  Fly   451 NPIHNGHALLMQDTRRQLLERGFKQPVLLLHPLGGWTKDDDVPLDVRMKQHQAVLDAGVLRREDT 515
            ||:||||||||.||||:|||.|:|.|:||||||||:||.||||||.|||||:.||:.|||..|.|
plant   250 NPVHNGHALLMTDTRRRLLEMGYKNPILLLHPLGGFTKADDVPLDWRMKQHEKVLEDGVLDPETT 314

  Fly   516 VLAIFPSPMMYAGPTEVQWHAKARMNAGANFYIVGRDPAGMPHPAKETYPDGNLYDATHGARVLK 580
            |::||||||.||||||||||||||:||||||||||||||||.||.::.    :||||.||.:||.
plant   315 VVSIFPSPMHYAGPTEVQWHAKARINAGANFYIVGRDPAGMGHPVEKR----DLYDADHGKKVLS 375

  Fly   581 MAQGLDSMEILPFRVAAYDKSASRMAFFEPKRKDEFEFISGTKMRTLAKTGASPPDGFMEPEAWR 645
            ||.||:.:.|||||||||||:..:||||:|.|..:|.||||||||||||...:||||||.|..|:
plant   376 MAPGLERLNILPFRVAAYDKTQGKMAFFDPSRPQDFLFISGTKMRTLAKNNENPPDGFMCPGGWK 440

  Fly   646 ILATYYQNL 654
            :|..||::|
plant   441 VLVDYYESL 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Papss	NP_730460.1	APS_kinase	73..228	CDD:279865
		sopT	270..648	CDD:273023	227/379 (60%)
		ATPS	279..650	CDD:173895	224/372 (60%)
APS1	NP_188929.1	sopT	53..444	CDD:273023	232/392 (59%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	322	1.000	Domainoid score	I273
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	460	1.000	Inparanoid score	I369
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D528280at2759
OrthoFinder	1	1.000	-	-		FOG0000913
OrthoInspector	1	1.000	-	-		otm3262
orthoMCL	1	0.900	-	-		OOG6_100343
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X525
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.920