DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Papss and papss1

DIOPT Version :9

Sequence 1:	NP_730460.1	Gene:	Papss / 40167	FlyBaseID:	FBgn0020389	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	NP_001006743.1	Gene:	papss1 / 448413	XenbaseID:	XB-GENE-947140	Length:	624	Species:	Xenopus tropicalis

Alignment Length:	617	Identity:	394/617 - (63%)
Similarity:	476/617 - (77%)	Gaps:	17/617 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 LQVATNVTEQKHHVTRETRGKNLGLCRGFRGCTVWLTGLSGAGKTSIAFELEAYLVSRGIPAYGL 108
            :|.|||||.|.|||:|..||:.:|...||||||||||||||||||:::..||.|||..|||.|.|
Frog    22 MQRATNVTYQAHHVSRNKRGQVVGARSGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTL 86

  Fly   109 DGDNIRTGLNKNLGFTPADREENIRRVGEVAKLFADSGVVAICSFVSPFADDREMARKIHKDAGL 173
            ||||||.||:|||||:..||||||||:.||||||||:|:|.|.||:||:|.||..||:||:.|.|
Frog    87 DGDNIRHGLSKNLGFSQEDREENIRRIAEVAKLFADAGLVCITSFISPYAKDRNNARQIHEAASL 151

  Fly   174 KFYEIFVDTPLDVCETRDVKGLYKKAREGVIKGFTGITQEYERPQMPELVVNTHGYTVRESTQKL 238
            .|||:|||.||.:||.|||||||||||.|.|||||||..|||:|:.||||:.|....|.:..|::
Frog   152 PFYEVFVDAPLYICEQRDVKGLYKKARAGEIKGFTGIDAEYEKPEAPELVLKTDSCDVNDCIQQV 216

  Fly   239 VTLLEQEGIIPRSLRDVDL---LPELYPSESIATEALRHEAESLQAIEISTVELQWVQVLAEGWA 300
            |.||::..|:|     ||.   :.|||..|: ..:..:.:||:|..:||:.|::|||||||||||
Frog   217 VELLQEMDIVP-----VDASYEVKELYVPEN-KLQLAKTDAETLPTLEINKVDMQWVQVLAEGWA 275

  Fly   301 YPLRGFMREDEYLQTLHFNTLQSGMDGSYRENHSVPIVLSATQADKDRLDGCSSLTLKYQGKAVA 365
            .||.|||||.||||.|||:.|   :||.. .|.||||||:||..||.||:||::..|.|:|..||
Frog   276 TPLNGFMREREYLQCLHFDCL---LDGGV-INLSVPIVLTATSDDKQRLEGCTAFALVYEGNRVA 336

  Fly   366 ILRRPEFYFQRKEERLARQFGTSNPNHPYSKQVYESGDYLVGGDLAVIERIRWEDGLDQYRLTPN 430
            |||.||||..|||||.|||:||:..:|||.|.|.|||::||||||.|::||.|.||||||||||.
Frog   337 ILRHPEFYEHRKEERCARQWGTTCKDHPYIKMVVESGEWLVGGDLQVLDRIYWNDGLDQYRLTPA 401

  Fly   431 ELRRRFKELNADAIFAFQLRNPIHNGHALLMQDTRRQLLERGFKQPVLLLHPLGGWTKDDDVPLD 495
            ||:::||::||||:||||||||:|||||||||||.:|||:||:::|||||||||||||||||||.
Frog   402 ELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLDRGYRRPVLLLHPLGGWTKDDDVPLM 466

  Fly   496 VRMKQHQAVLDAGVLRREDTVLAIFPSPMMYAGPTEVQWHAKARMNAGANFYIVGRDPAGMPHPA 560
            .|||||.|||..|||..|.||:||||||||||||||||||.:|||.|||||||||||||||||||
Frog   467 WRMKQHAAVLKEGVLDPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPA 531

  Fly   561 KETYPDGNLYDATHGARVLKMAQGLDSMEILPFRVAAYDKSASRMAFFEPKRKDEFEFISGTKMR 625
              |..|  ||:.||||:||.||.||.|:||:|||||||:|....|.:|:....::|:|||||:||
Frog   532 --TGKD--LYEPTHGAKVLTMAPGLISLEIVPFRVAAYNKKKKCMDYFDSAHPEDFDFISGTRMR 592

  Fly   626 TLAKTGASPPDGFMEPEAWRILATYYQNLPQS 657
            .||:.|.:||||||.|.||.:|..|||:|.::
Frog   593 RLAREGQNPPDGFMAPSAWTVLKEYYQSLEKA 624

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Papss	NP_730460.1	APS_kinase	73..228	CDD:279865	109/154 (71%)
		sopT	270..648	CDD:273023	251/377 (67%)
		ATPS	279..650	CDD:173895	250/370 (68%)
papss1	NP_001006743.1	APSK	54..204	CDD:238985	105/149 (70%)
papss1	NP_001006743.1	ATPS	254..617	CDD:173895	250/370 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	336	1.000	Domainoid score	I1128
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H81740
Inparanoid	1	1.050	776	1.000	Inparanoid score	I523
OMA	1	1.010	-	-		QHG52346
OrthoDB	1	1.010	-	-		D261243at33208
OrthoFinder	1	1.000	-	-		FOG0000913
OrthoInspector	1	1.000	-	-		otm49019
Panther	1	1.100	-	-	O	PTHR11055
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R633
SonicParanoid	1	1.000	-	-		X525
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110