Protein Alignment Papss and Papss1

DIOPT Version :10

• Sequence 1: NP_730460.1
• Gene: Papss / 40167
• FlyBaseID: FBgn0020389
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: NP_001381988.1
• Gene: Papss1 / 295443
• RGDID: 1308081
• Length: 624
• Species: Rattus norvegicus
• Alignment Length: 617
• Identity: 391/617 - (63%)
• Similarity: 480/617 - (77%)
• Gaps: 17/617 - (2%)

  Fly    44 LQVATNVTEQKHHVTRETRGKNLGLCRGFRGCTVWLTGLSGAGKTSIAFELEAYLVSRGIPAYGL 108
            :|.|||||.|.|||:|..||:.:|...||||||||||||||||||:::..||.|||..|||.|.|
  Rat    22 MQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTL 86

  Fly   109 DGDNIRTGLNKNLGFTPADREENIRRVGEVAKLFADSGVVAICSFVSPFADDREMARKIHKDAGL 173
            ||||||.||||||||:|.|||||:||:.||||||||:|:|.|.||:||:..||..||:||:.|.|
  Rat    87 DGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASL 151

  Fly   174 KFYEIFVDTPLDVCETRDVKGLYKKAREGVIKGFTGITQEYERPQMPELVVNTHGYTVRESTQKL 238
            .|:|:|||.||.|||.|||||||||||.|.|||||||..|||:|:.||||:.|....|.:..|::
  Rat   152 PFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQV 216

  Fly   239 VTLLEQEGIIPRSLRDVDL---LPELYPSESIATEALRHEAESLQAIEISTVELQWVQVLAEGWA 300
            |.||::..|:|     ||.   :.|||..|: .....:.:||:|.|::|:.|::|||||||||||
  Rat   217 VELLQERDIVP-----VDASYEVKELYVPEN-KLHLAKTDAEALPALKINKVDMQWVQVLAEGWA 275

  Fly   301 YPLRGFMREDEYLQTLHFNTLQSGMDGSYRENHSVPIVLSATQADKDRLDGCSSLTLKYQGKAVA 365
            .||.|||||.||||.|||:.|   :||.. .|.||||||:|||.||:|||||::..|.|:|:.||
  Rat   276 TPLNGFMREREYLQCLHFDCL---LDGGV-INLSVPIVLTATQEDKERLDGCTAFALVYEGRRVA 336

  Fly   366 ILRRPEFYFQRKEERLARQFGTSNPNHPYSKQVYESGDYLVGGDLAVIERIRWEDGLDQYRLTPN 430
            |||.|||:..|||||.|||:||:..:|||.|.:.|.||:|:||||.|::||.|.||||||||||.
  Rat   337 ILRNPEFFEHRKEERCARQWGTTCRSHPYIKMILEQGDWLIGGDLQVLDRIYWNDGLDQYRLTPA 401

  Fly   431 ELRRRFKELNADAIFAFQLRNPIHNGHALLMQDTRRQLLERGFKQPVLLLHPLGGWTKDDDVPLD 495
            ||:::||::||||:||||||||:|||||||||||.:||||||:::|||||||||||||||||||.
  Rat   402 ELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLM 466

  Fly   496 VRMKQHQAVLDAGVLRREDTVLAIFPSPMMYAGPTEVQWHAKARMNAGANFYIVGRDPAGMPHPA 560
            .|||||.|||:.|:|..|.||:||||||||||||||||||.:|||.||||||||||||||||||
  Rat   467 WRMKQHAAVLEEGILNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHP- 530

  Fly   561 KETYPDGNLYDATHGARVLKMAQGLDSMEILPFRVAAYDKSASRMAFFEPKRKDEFEFISGTKMR 625
             ||..|  ||:.||||:||.||.||.::||:|||||||:|...||.:::....::|||||||:||
  Rat   531 -ETGKD--LYEPTHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSDHHEDFEFISGTRMR 592

  Fly   626 TLAKTGASPPDGFMEPEAWRILATYYQNLPQS 657
            .||:.|..||:|||.|:||.:|..||::|.::
  Rat   593 KLAREGQKPPEGFMAPKAWTVLVEYYKSLEKA 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Papss	NP_730460.1	CysC	55..249	CDD:440295	124/193 (64%)
		ATPS	279..650	CDD:173895	248/370 (67%)
Papss1	NP_001381988.1	CysC	33..227	CDD:440295	124/193 (64%)
		ATPS	254..617	CDD:173895	248/370 (67%)