DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Papss and sua1

DIOPT Version :9

Sequence 1:	NP_730460.1	Gene:	Papss / 40167	FlyBaseID:	FBgn0020389	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	NP_595662.2	Gene:	sua1 / 2540422	PomBaseID:	SPBC27.08c	Length:	490	Species:	Schizosaccharomyces pombe

Alignment Length:	409	Identity:	127/409 - (31%)
Similarity:	195/409 - (47%)	Gaps:	42/409 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   257 LLPELYPSESIATEALRHEAESLQAIEISTVELQWVQVLAEGWAYPLRGFMREDEYLQTLHFNTL 321
            ||.:|...::...|.|..||.||..|.:|..:...|:::..|...||.|||.:.:||..:....|
pombe     5 LLKDLNARDAPLREQLEQEATSLPKIVLSERQFCDVELILNGGFSPLDGFMNQKDYLNVVENLRL 69

  Fly   322 QSGMDGSYRENHSVPIVLSATQADKDRL---DGCSSLTLKYQGKAVAILRRPEFYFQRKEERLAR 383
            .:|      |...:||.|...::..|.|   |..:.|..:.....:|||...:.|...|.....:
pombe    70 STG------EVFPIPITLDLNESQADSLKAGDRVALLDPRDGQTVIAILTVEDKYTPDKANEAEK 128

  Fly   384 QFGTSNPNHPYSKQVY-ESGDYLVGGDLAVIERIRWEDGLDQYRLTPNELRRRFKELNADAIFAF 447
            .||.::..||....:: .:|:..|||.|..:..||..|.: :||.:|.:||..|:..|.:.:.||
pombe   129 VFGANDRAHPAVDYLFGRAGNVYVGGKLQAVTPIRHFDFV-EYRYSPAQLRSDFQRNNWNRVVAF 192

  Fly   448 QLRNPIHNGHALLMQDTRRQLLERGFKQ--PVLLLHPLGGWTKDDDVPLDVRMKQHQAVLDAGVL 510
            |.|||:|..|        |:|..|..||  ..:|:||:.|.||..|:....|::.::|:|..  .
pombe   193 QTRNPMHRAH--------RELTVRAAKQHGARVLIHPVVGMTKPGDIDHFTRVRVYEAILQR--Y 247

  Fly   511 RREDTVLAIFPSPMMYAGPTEVQWHAKARMNAGANFYIVGRDPAGMPHPAKETYPDG--NLYDAT 573
            .:....|::.|..|..|||.|..|||..|.|.||:.:|:|||.||   |.|.:..:.  ..|||.
pombe   248 PKGSAKLSLLPLAMRMAGPREALWHAIIRKNYGASHFIIGRDHAG---PGKNSQGEDFYGPYDAQ 309

  Fly   574 HGARVLKMAQGLDSMEILPFRVAAY--DKSASRMAFFEPKRKDE----FEFISGTKMRTLAKTGA 632
            :  .|.:.||.: .:.|:||::..|  |:.     .::|..|.|    ...||||::|...:.||
pombe   310 Y--LVEQYAQEI-GITIVPFQMMTYLPDED-----IYKPVDKVEPGTRTLNISGTELRRRLRVGA 366

  Fly   633 SPPDGFMEPEAWRILATYY 651
            :.|:.|..||...||...|
pombe   367 NIPEWFSYPEVVAILRQSY 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Papss	NP_730460.1	APS_kinase	73..228	CDD:279865
		sopT	270..648	CDD:273023	122/391 (31%)
		ATPS	279..650	CDD:173895	118/384 (31%)
sua1	NP_595662.2	sopT	6..382	CDD:273023	124/403 (31%)
sua1	NP_595662.2	ATPS	27..384	CDD:173895	118/384 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	101	1.000	Domainoid score	I1795
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	148	1.000	Inparanoid score	I1325
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100343
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.860