Protein Alignment Papss and pps-1

DIOPT Version :9

• Sequence 1: NP_730460.1
• Gene: Papss / 40167
• FlyBaseID: FBgn0020389
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: NP_001293960.1
• Gene: pps-1 / 177893
• WormBaseID: WBGene00004091
• Length: 654
• Species: Caenorhabditis elegans
• Alignment Length: 661
• Identity: 359/661 - (54%)
• Similarity: 463/661 - (70%)
• Gaps: 35/661 - (5%)

  Fly    17 NNNNSACCAASPKRSCLPSVEKPEDACLQ-VATNVTEQKHHVTRETRGKNLGLCRGFRGCTVWLT 80
            ||...|          :|.::||..:.|. .:||:|.|:|.::||.|...:|...||||||:|.|
 Worm     8 NNEGDA----------MPMLKKPRYSSLSGQSTNITYQEHTISREERAAAVGRHEGFRGCTIWFT 62

  Fly    81 GLSGAGKTSIAFELEAYLVSRGIPAYGLDGDNIRTGLNKNLGFTPADREENIRRVGEVAKLFADS 145
            ||||||||:|:|.||..|...|||.|||||||||.||.|||||:..||:||||||.|||||||||
 Worm    63 GLSGAGKTTISFALERTLNKLGIPCYGLDGDNIRHGLCKNLGFSKEDRQENIRRVAEVAKLFADS 127

  Fly   146 GVVAICSFVSPFADDREMARKIHKDAGLKFYEIFVDTPLDVCETRDVK--GLYKKAREGVIKGFT 208
            |::.:.:|:|||.:||..|||||:...:||.|:.|.|.|:|||.||.|  .||||||.|.|.|||
 Worm   128 GMICLAAFISPFQEDRLDARKIHESENVKFIEVHVSTTLEVCEQRDPKPSELYKKARAGQILGFT 192

  Fly   209 GITQEYERPQMPELVVNTHGYTVRESTQKLVTLLEQEGIIPRSLRDVDLLPELYPSESIATEALR 273
            ||...||.|:..|::::.....|::..||::..||.:|::|..:.||..:.||:.|:.:....|.
 Worm   193 GIDSAYEPPENAEIILDAGKDGVQQCVQKVLDHLESKGLLPEQIPDVPAVRELFVSDDLTVAELL 257

  Fly   274 HEAESLQAIEISTVELQWVQVLAEGWAYPLRGFMREDEYLQTLHFNTLQS--------GMDGSYR 330
            .|:::|..:|::.|:|||:||||||||.||.|||||.:|||::||..|..        |.....:
 Worm   258 KESQNLPTVELTKVDLQWLQVLAEGWATPLSGFMRERQYLQSMHFGQLLDLKHKVAFVGEKSDDK 322

  Fly   331 E---------NHSVPIVLSATQADKDRLDGCSSLTLKYQGKAVAILRRPEFYFQRKEERLARQFG 386
            |         |.|:||||..:...|..|:|.:.:.|||.|:..|||..||.:..||:||:.||||
 Worm   323 EDSWPMMDDINQSIPIVLPISDDVKKGLEGVTRIALKYNGQVYAILSDPEIFEHRKDERVCRQFG 387

  Fly   387 TSNPNHPYSKQVYESGDYLVGGDLAVIERIRWEDGLDQYRLTPNELRRRFKELNADAIFAFQLRN 451
            |::|.||...||.|||::|:|||:||:::|::.||||:||.||||||..|.|.||||:|||||||
 Worm   388 TNDPRHPAVAQVLESGNWLLGGDVAVVQKIQFNDGLDKYRKTPNELRAIFAEKNADAVFAFQLRN 452

  Fly   452 PIHNGHALLMQDTRRQLLERGFKQPVLLLHPLGGWTKDDDVPLDVRMKQHQAVLDAGVLRREDTV 516
            ||||||||||:|||.:||.. .|.|:||||||||||||||||||:|:|||:||:...||..|.||
 Worm   453 PIHNGHALLMRDTREKLLAE-HKNPILLLHPLGGWTKDDDVPLDIRIKQHEAVIAERVLDPEWTV 516

  Fly   517 LAIFPSPMMYAGPTEVQWHAKARMNAGANFYIVGRDPAGMPHPAKETYPDGNLYDATHGARVLKM 581
            |:||||||||||||||||||::|:.||...|||||||||:..|..   ||. ||:.||||:||.|
 Worm   517 LSIFPSPMMYAGPTEVQWHARSRIAAGIQHYIVGRDPAGIQKPGS---PDA-LYETTHGAKVLSM 577

  Fly   582 AQGLDSMEILPFRVAAYDKSASRMAFFEPKRKDEFEFISGTKMRTLAKTGASPPDGFMEPEAWRI 646
            |.||.::.|||||||||||:|.:|:||:..||::||.|||||||.||:.|.:||:|||.|.||.:
 Worm   578 APGLSALHILPFRVAAYDKTAKKMSFFDTSRKEDFENISGTKMRGLARNGDTPPEGFMAPTAWEV 642

  Fly   647 LATYYQNLPQS 657
            ||.||::|..|
 Worm   643 LAGYYKSLQNS 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Papss	NP_730460.1	APS_kinase	73..228	CDD:279865	96/156 (62%)
		sopT	270..648	CDD:273023	227/394 (58%)
		ATPS	279..650	CDD:173895	227/387 (59%)
pps-1	NP_001293960.1	APS_kinase	55..212	CDD:279865	96/156 (62%)
		sopT	237..644	CDD:273023	232/411 (56%)
		ATPS	263..646	CDD:173895	227/387 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164002
Domainoid	1	1.000	311	1.000	Domainoid score	I719
eggNOG	1	0.900	-	-		E1_COG0529
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	697	1.000	Inparanoid score	I350
Isobase	1	0.950	-	0	Normalized mean entropy	S866
OMA	1	1.010	-	-		QHG52346
OrthoDB	1	1.010	-	-		D261243at33208
OrthoFinder	1	1.000	-	-		FOG0000913
OrthoInspector	1	1.000	-	-		oto18108
orthoMCL	1	0.900	-	-		OOG6_100343
Panther	1	1.100	-	-	LDO	PTHR11055
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R633
SonicParanoid	1	1.000	-	-		X525
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.790