Protein Alignment Papss and pps-1

DIOPT Version :10

• Sequence 1: NP_730460.1
• Gene: Papss / 40167
• FlyBaseID: FBgn0020389
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: NP_001293960.1
• Gene: pps-1 / 177893
• WormBaseID: WBGene00004091
• Length: 654
• Species: Caenorhabditis elegans
• Alignment Length: 661
• Identity: 359/661 - (54%)
• Similarity: 463/661 - (70%)
• Gaps: 35/661 - (5%)

  Fly    17 NNNNSACCAASPKRSCLPSVEKPEDACLQ-VATNVTEQKHHVTRETRGKNLGLCRGFRGCTVWLT 80
            ||...|          :|.::||..:.|. .:||:|.|:|.::||.|...:|...||||||:|.|
 Worm     8 NNEGDA----------MPMLKKPRYSSLSGQSTNITYQEHTISREERAAAVGRHEGFRGCTIWFT 62

  Fly    81 GLSGAGKTSIAFELEAYLVSRGIPAYGLDGDNIRTGLNKNLGFTPADREENIRRVGEVAKLFADS 145
            ||||||||:|:|.||..|...|||.|||||||||.||.|||||:..||:||||||.|||||||||
 Worm    63 GLSGAGKTTISFALERTLNKLGIPCYGLDGDNIRHGLCKNLGFSKEDRQENIRRVAEVAKLFADS 127

  Fly   146 GVVAICSFVSPFADDREMARKIHKDAGLKFYEIFVDTPLDVCETRDVK--GLYKKAREGVIKGFT 208
            |::.:.:|:|||.:||..|||||:...:||.|:.|.|.|:|||.||.|  .||||||.|.|.|||
 Worm   128 GMICLAAFISPFQEDRLDARKIHESENVKFIEVHVSTTLEVCEQRDPKPSELYKKARAGQILGFT 192

  Fly   209 GITQEYERPQMPELVVNTHGYTVRESTQKLVTLLEQEGIIPRSLRDVDLLPELYPSESIATEALR 273
            ||...||.|:..|::::.....|::..||::..||.:|::|..:.||..:.||:.|:.:....|.
 Worm   193 GIDSAYEPPENAEIILDAGKDGVQQCVQKVLDHLESKGLLPEQIPDVPAVRELFVSDDLTVAELL 257

  Fly   274 HEAESLQAIEISTVELQWVQVLAEGWAYPLRGFMREDEYLQTLHFNTLQS--------GMDGSYR 330
            .|:::|..:|::.|:|||:||||||||.||.|||||.:|||::||..|..        |.....:
 Worm   258 KESQNLPTVELTKVDLQWLQVLAEGWATPLSGFMRERQYLQSMHFGQLLDLKHKVAFVGEKSDDK 322

  Fly   331 E---------NHSVPIVLSATQADKDRLDGCSSLTLKYQGKAVAILRRPEFYFQRKEERLARQFG 386
            |         |.|:||||..:...|..|:|.:.:.|||.|:..|||..||.:..||:||:.||||
 Worm   323 EDSWPMMDDINQSIPIVLPISDDVKKGLEGVTRIALKYNGQVYAILSDPEIFEHRKDERVCRQFG 387

  Fly   387 TSNPNHPYSKQVYESGDYLVGGDLAVIERIRWEDGLDQYRLTPNELRRRFKELNADAIFAFQLRN 451
            |::|.||...||.|||::|:|||:||:::|::.||||:||.||||||..|.|.||||:|||||||
 Worm   388 TNDPRHPAVAQVLESGNWLLGGDVAVVQKIQFNDGLDKYRKTPNELRAIFAEKNADAVFAFQLRN 452

  Fly   452 PIHNGHALLMQDTRRQLLERGFKQPVLLLHPLGGWTKDDDVPLDVRMKQHQAVLDAGVLRREDTV 516
            ||||||||||:|||.:||.. .|.|:||||||||||||||||||:|:|||:||:...||..|.||
 Worm   453 PIHNGHALLMRDTREKLLAE-HKNPILLLHPLGGWTKDDDVPLDIRIKQHEAVIAERVLDPEWTV 516

  Fly   517 LAIFPSPMMYAGPTEVQWHAKARMNAGANFYIVGRDPAGMPHPAKETYPDGNLYDATHGARVLKM 581
            |:||||||||||||||||||::|:.||...|||||||||:..|..   ||. ||:.||||:||.|
 Worm   517 LSIFPSPMMYAGPTEVQWHARSRIAAGIQHYIVGRDPAGIQKPGS---PDA-LYETTHGAKVLSM 577

  Fly   582 AQGLDSMEILPFRVAAYDKSASRMAFFEPKRKDEFEFISGTKMRTLAKTGASPPDGFMEPEAWRI 646
            |.||.::.|||||||||||:|.:|:||:..||::||.|||||||.||:.|.:||:|||.|.||.:
 Worm   578 APGLSALHILPFRVAAYDKTAKKMSFFDTSRKEDFENISGTKMRGLARNGDTPPEGFMAPTAWEV 642

  Fly   647 LATYYQNLPQS 657
            ||.||::|..|
 Worm   643 LAGYYKSLQNS 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Papss	NP_730460.1	CysC	55..249	CDD:440295	109/195 (56%)
		ATPS	279..650	CDD:173895	227/387 (59%)
pps-1	NP_001293960.1	CysC	37..233	CDD:440295	109/195 (56%)
		ATPS	263..646	CDD:173895	227/387 (59%)