Protein Alignment trc and YPK1

DIOPT Version :10

• Sequence 1: NP_001262071.1
• Gene: trc / 40165
• FlyBaseID: FBgn0003744
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_012796.1
• Gene: YPK1 / 853733
• SGDID: S000001609
• Length: 680
• Species: Saccharomyces cerevisiae
• Alignment Length: 351
• Identity: 125/351 - (35%)
• Similarity: 193/351 - (54%)
• Gaps: 54/351 - (15%)

  Fly    79 EYLRLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERD 143
            :|...:...|.::||:.|||||:|:||:|..|:||||..|||:|.:||:.::.|.:|.|..|||.
Yeast   333 DYKPSRNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERT 397

  Fly   144 VLVEADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIH 208
            ||...|..::|.:.:|||.|..||.::.|:.||::...|.|:........:||.:|...|:|::|
Yeast   398 VLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLH 462

  Fly   209 KLGFIHRDIKPDNLLLDARGHLKLSDFGLC-TGLKKSHRTDFYRDLSQAKPSDFIGTCASLSCSP 272
            ||..::||:||:|:|||.:||:.|.||||| ..:|...:||.:                   |
Yeast   463 KLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTF-------------------C-- 506

  Fly   273 MDSKRRAESWKRNRRALAYSTVGTPDYIAPEVFLQTGYGPACDWWSLGVIMYEMLMGYPPFCSDN 337
                                  |||:|:|||:.|..||..|.|||:|||::||||.|.||:..::
Yeast   507 ----------------------GTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDED 549

  Fly   338 PQDTYRKVMNWRETLIFPPEIPISEEAKETIINFCC-EADRRLGSQRGLEDLKSVPFFRGVDWEH 401
            ....|:|::  :|.|:||.  ....:||:.:|.... :..|||| ..|.:::::.|||..:.|:.
Yeast   550 VPKMYKKIL--QEPLVFPD--GFDRDAKDLLIGLLSRDPTRRLG-YNGADEIRNHPFFSQLSWKR 609

  Fly   402 IRER---PAAIPVEVRSIDDTSNFDE 424
            :..:   |...|....|: |||||||
Yeast   610 LLMKGYIPPYKPAVSNSM-DTSNFDE 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trc	NP_001262071.1	MobB_Trc-like	24..88	CDD:439274	1/8 (13%)
		STKc_NDR_like	91..455	CDD:270750	123/339 (36%)
YPK1	NP_012796.1	YPK1_N_like	116..342	CDD:212165	1/8 (13%)
		Protein Kinases, catalytic domain	352..663	CDD:473864	119/332 (36%)