Protein Alignment trc and DBF2

DIOPT Version :10

• Sequence 1: NP_001262071.1
• Gene: trc / 40165
• FlyBaseID: FBgn0003744
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_011606.3
• Gene: DBF2 / 852984
• SGDID: S000003324
• Length: 572
• Species: Saccharomyces cerevisiae
• Alignment Length: 426
• Identity: 137/426 - (32%)
• Similarity: 228/426 - (53%)
• Gaps: 22/426 - (5%)

  Fly    15 RFSDHTLDKATKAKVT------LENY---YSNLVTQYGERKQRLAKLEAQLKDESLSEAQRQEKR 70
            :|.:......|:..|:      ||:|   :..::::....||.|..|:.|.:..:..:.:..|:.
Yeast    90 KFYERATSNKTQRVVSVCKMYFLEHYCDMFDYVISRRQRTKQVLEYLQQQSQLPNSDQIKLNEEW 154

  Fly    71 LQHAQKETEYLRLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQV 135
            ..:.|:|.:.||.:||:....|||.:..:|:|.:|:|.|.:||||..|.|:|:|.|..:.:..:.
Yeast   155 SSYLQREHQVLRKRRLKPKNRDFEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNET 219

  Fly   136 AHVRAERDVLVEADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISET 200
            .||..|||:|.....:|:||:.|:|||..:|||.|||:||||..|||:....|.....:|||||.
Yeast   220 KHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEM 284

  Fly   201 ALAIDSIHKLGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYR-DLSQAKPSDFIGT 264
            ..|::::|.||:.|||:||:|.|:||:||:||:||||..|...:.|.:..: .|.:.|..:|
Yeast   285 FCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEF--- 346

  Fly   265 CASLSCSPMDSKRRAESWKRNRRA-LAYSTVGTPDYIAPEVFLQTGYGPACDWWSLGVIMYEMLM 328
             .:.:...::.:|:..:..|.:.. .|.|.||:|||:|.||.....|....|:||||.:::|.|:
Yeast   347 -PAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLV 410

  Fly   329 GYPPFCSDNPQDTYRKVMNWRETLIFPPE----IPISEEAKETIINFCCEADRRLGSQRGLEDLK 389
            ||.||...:..:||..:..|::||..|.:    ...|:...:.|.....:...||   |..|.:|
Yeast   411 GYTPFSGSSTNETYDNLRRWKQTLRRPRQSDGRAAFSDRTWDLITRLIADPINRL---RSFEHVK 472

  Fly   390 SVPFFRGVDWEHIRERPAAIPVEVRSIDDTSNFDEF 425
            .:.:|..:::..:|........::.|..|...||:|
Yeast   473 RMSYFADINFSTLRSMIPPFTPQLDSETDAGYFDDF 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trc	NP_001262071.1	MobB_Trc-like	24..88	CDD:439274	17/72 (24%)
		STKc_NDR_like	91..455	CDD:270750	119/341 (35%)
DBF2	NP_011606.3	MobB_Sid2p-like	85..172	CDD:439271	18/81 (22%)
		STKc_Sid2p_like	165..547	CDD:270751	123/351 (35%)