DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trc and Cit

DIOPT Version :9

Sequence 1:	NP_001262071.1	Gene:	trc / 40165	FlyBaseID:	FBgn0003744	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	XP_038945746.1	Gene:	Cit / 83620	RGDID:	70878	Length:	2114	Species:	Rattus norvegicus

Alignment Length:	383	Identity:	138/383 - (36%)
Similarity:	212/383 - (55%)	Gaps:	56/383 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 LKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVE 147
            |:.|:..|.|||...::|.|.|.||::|::|.||.|||||:::||.:..:|||:....||::|.:
  Rat    87 LRELQPSVRDFEVRSLVGCGHFAEVQVVREKATGDVYAMKIMKKAALRAQEQVSFFEEERNILSQ 151

  Fly   148 ADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMK-KDTLSEEGTQFYISETALAIDSIHKLG 211
            :...|:.::.|:|||..||||:||:.||||:::||.: :|.|.|...|||::|..||:.|:|::|
  Rat   152 STSPWIPQLQYAFQDKNNLYLVMEYQPGGDLLSLLNRYEDQLDENMIQFYLAELILAVHSVHQMG 216

  Fly   212 FIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSDFIGTCASLSCSPMDSK 276
            ::||||||:|:|:|..||:||.||                           |:.|.::.:.:|:|
  Rat   217 YVHRDIKPENILIDRTGHIKLVDF---------------------------GSAAKMNSNKVDAK 254

  Fly   277 RRAESWKRNRRALAYSTVGTPDYIAPEVFL------QTGYGPACDWWSLGVIMYEMLMGYPPFCS 335
                           ..:|||||:||||..      :..||..|||||:||:.||||.|..||..
  Rat   255 ---------------LPIGTPDYMAPEVLTVMNEDRRGTYGLDCDWWSVGVVAYEMLYGKTPFTE 304

  Fly   336 DNPQDTYRKVMNWRETLIFPPEIPISEEAKETIINFCCEADRRLGSQRGLEDLKSVPFFRGVDWE 400
            .....|:..:||::..|.||.:..:|.|..:.|.:..|....||    ..|.|...|||...||.
  Rat   305 GTSARTFNNIMNFQRFLKFPDDPKVSSELLDLIQSLLCVQKERL----KFEGLCCHPFFARTDWN 365

  Fly   401 HIRERPAAIPVEVRSIDDTSNFDEFPDVSLEIPSAP--IPQGGEIAKDWVFINYTYKR 456
            :||..|......::|.|||||||| |:.:..:.|:|  :...|...::..|:.::|.:
  Rat   366 NIRNSPPPFVPTLKSDDDTSNFDE-PEKNSWVSSSPCQLSPSGFSGEELPFVGFSYSK 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trc	NP_001262071.1	OmpH	16..>85	CDD:214922	1/1 (100%)
trc	NP_001262071.1	STKc_NDR_like	91..455	CDD:270750	134/372 (36%)
Cit	XP_038945746.1	STKc_CRIK	96..421	CDD:270752	134/371 (36%)
		Smc	472..1363	CDD:224117
		CRIK	1429..1484	CDD:410364
		PH	1514..1633	CDD:395117
		CNH	1678..1974	CDD:214481
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920