DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trc and cdc42bpb

DIOPT Version :9

Sequence 1:	NP_001262071.1	Gene:	trc / 40165	FlyBaseID:	FBgn0003744	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	XP_004917233.2	Gene:	cdc42bpb / 733471	XenbaseID:	XB-GENE-1005934	Length:	1731	Species:	Xenopus tropicalis

Alignment Length:	443	Identity:	179/443 - (40%)
Similarity:	246/443 - (55%)	Gaps:	77/443 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 KQRLAKLEAQLKD-----------ESLSE------AQRQEKRLQHAQKETEYLR--------LKR 85
            |.||.|||..|.|           |:|.:      .:.....|:..:..:|:|.        ||.
Frog     4 KVRLKKLEQLLLDGPQRNEAALSVETLLDVLLCLYTECSHSTLRRDKYVSEFLEWAKPFTDLLKG 68

  Fly    86 LRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVEADH 150
            ::|..:|||.:|||||||||||.:|:.|.|..:||||:|.|.:||::.:.|..|.||:|||..|.
Frog    69 MQLHRDDFEIIKVIGRGAFGEVAVVRLKSTERIYAMKILNKWEMLKRAETACFREERNVLVNGDC 133

  Fly   151 QWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMK-KDTLSEEGTQFYISETALAIDSIHKLGFIH 214
            ||:..::|:|||...|||:|::..|||::|||.| :|.|.|:..:||::|..|||.|||:|.::|
Frog   134 QWITSLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVLAIHSIHQLHYVH 198

  Fly   215 RDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSDFIGTCASLSCSPMDSKRRA 279
            |||||||:|||..||::|:|||                                ||..|::....
Frog   199 RDIKPDNVLLDMNGHIRLADFG--------------------------------SCLKMNADGTV 231

  Fly   280 ESWKRNRRALAYSTVGTPDYIAPEVF--LQTG---YGPACDWWSLGVIMYEMLMGYPPFCSDNPQ 339
            :|      ::|   |||||||:||:.  ::.|   |||.||||||||.|||||.|..||.:::..
Frog   232 QS------SVA---VGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLV 287

  Fly   340 DTYRKVMNWRETLIFPPEI-PISEEAKETIINFCCEADRRLGSQRGLEDLKSVPFFRGVDWEHIR 403
            :||.|:||..|...||..| .:||.||:.|....|..:|||| |.|::|.|:.|||.|:||::||
Frog   288 ETYGKIMNHEERFQFPSHIGDVSESAKDVIQRLICSRERRLG-QNGIDDFKAHPFFEGIDWDNIR 351

  Fly   404 ERPAAIPVEVRSIDDTSNFDEFPDVSLEIPSA--PIPQGGEIAKDWVFINYTY 454
            ...|....:|.|..||||||...|| |..|..  |....|.......|:.:||
Frog   352 NLEAPYIPDVSSPYDTSNFDVDDDV-LRNPEVIPPSTHSGFSGFHLPFVGFTY 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trc	NP_001262071.1	OmpH	16..>85	CDD:214922	14/63 (22%)
trc	NP_001262071.1	STKc_NDR_like	91..455	CDD:270750	163/373 (44%)
cdc42bpb	XP_004917233.2	STKc_MRCK_beta	3..411	CDD:270774	179/443 (40%)
		Smc	<375..804	CDD:224117	9/30 (30%)
		KELK	528..606	CDD:406277
		DMPK_coil	895..944	CDD:117396
		C1_MRCKbeta	1044..1096	CDD:410415
		PH_MRCK	1103..1238	CDD:269949
		CNH	1264..1529	CDD:395630
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010