DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trc and cdc42bpaa

DIOPT Version :9

Sequence 1:	NP_001262071.1	Gene:	trc / 40165	FlyBaseID:	FBgn0003744	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	XP_021322967.1	Gene:	cdc42bpaa / 567912	ZFINID:	ZDB-GENE-120727-12	Length:	1757	Species:	Danio rerio

Alignment Length:	409	Identity:	173/409 - (42%)
Similarity:	240/409 - (58%)	Gaps:	56/409 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 DESLSEAQRQEKR----LQHAQKETEYLRLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHV 118
            ||..:...|:||.    |:.|:..|.  ::|::||..||||.||||||||||||.:|:.|.:..|
Zfish    40 DECTNSPLRREKNVAEFLEWAKPFTS--KVKQMRLHKEDFEILKVIGRGAFGEVAVVKVKSSDKV 102

  Fly   119 YAMKVLRKADMLEKEQVAHVRAERDVLVEADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLM 183
            :|||:|.|.:||::.:.|..|.||||||..|.||:..::|:|||...|||:|::..|||::|||.
Zfish   103 FAMKILNKWEMLKRAETACFREERDVLVNGDSQWITTLHYAFQDDNFLYLVMDYYVGGDLLTLLS 167

  Fly   184 K-KDTLSEEGTQFYISETALAIDSIHKLGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRT 247
            | :|.|.|:..:||::|..|||||:|:|.::||||||||:|:|..||::|:|||.|..|.:.
Zfish   168 KFEDRLPEDMARFYLAEMVLAIDSVHQLHYVHRDIKPDNILIDVNGHIRLADFGSCLKLTED--- 229

  Fly   248 DFYRDLSQAKPSDFIGTCASLSCSPMDSKRRAESWKRNRRALAYSTVGTPDYIAPEVF--LQTG- 309
                           ||..|                    ::|   |||||||:||:.  ::.|
Zfish   230 ---------------GTVQS--------------------SVA---VGTPDYISPEILQAMEDGK 256

  Fly   310 --YGPACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKVMNWRETLIFPPEI-PISEEAKETIINF 371
              |||.||||||||.|||||.|..||.:::..:||.|:||.:|...||.:: .:||.||:.|...
Zfish   257 GKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQMTDVSENAKDLIRRL 321

  Fly   372 CCEADRRLGSQRGLEDLKSVPFFRGVDWEHIRERPAAIPVEVRSIDDTSNFDEFPDVSLEIPSAP 436
            .|..:.||| |.|:||.|..|||.|:||::||...|....||.|..||||||...|......:.|
Zfish   322 ICCREHRLG-QNGIEDFKQHPFFSGIDWQNIRNCDAPYIPEVSSPSDTSNFDVDDDCLKNTETMP 385

  Fly   437 IPQGGEIAKDWV-FINYTY 454
            .|.....:...: |:.:||
Zfish   386 PPSHTAFSGHHLPFVGFTY 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trc	NP_001262071.1	OmpH	16..>85	CDD:214922	8/30 (27%)
trc	NP_001262071.1	STKc_NDR_like	91..455	CDD:270750	162/372 (44%)
cdc42bpaa	XP_021322967.1	PKc_like	4..412	CDD:328722	173/409 (42%)
		SbcC	<433..>926	CDD:223496
		KELK	528..606	CDD:318090
		C1_1	1009..1059	CDD:278556
		PH_MRCK	1068..1203	CDD:269949
		CNH	1229..1495	CDD:307087
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920