DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trc and Akt1

DIOPT Version :9

Sequence 1:	NP_001262071.1	Gene:	trc / 40165	FlyBaseID:	FBgn0003744	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	NP_732113.3	Gene:	Akt1 / 41957	FlyBaseID:	FBgn0010379	Length:	611	Species:	Drosophila melanogaster

Alignment Length:	382	Identity:	125/382 - (32%)
Similarity:	197/382 - (51%)	Gaps:	66/382 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 RLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVEADHQ 151
            ::.:|:||.|||:|:|.||:|.|.::|.|..:||:|:|:|..:::|::|||...|..||...:|.
  Fly   260 KVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNHP 324

  Fly   152 WVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIHKLGFIHRD 216
            :::.:.||||....|..:|:::.||::...|..:...:|:.|:||.:|...|:..:|..|.|:||
  Fly   325 FLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRD 389

  Fly   217 IKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSDFIGTCASLSCSPMDSKRRAES 281
            :|.:|||||..||:|::|||||                  |.....|......|
  Fly   390 LKLENLLLDKDGHIKVADFGLC------------------KEDITYGRTTKTFC----------- 425

  Fly   282 WKRNRRALAYSTVGTPDYIAPEVFLQTGYGPACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKVM 346
                         |||:|:||||.....||.|.|||..||:||||:.|..||        |.:..
  Fly   426 -------------GTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPF--------YNRDH 469

  Fly   347 NWRETLIFPPEIP----ISEEAKETIINFCC-EADRRLGSQRGLEDLKSV---PFFRGVDWEH-- 401
            :...|||...|:.    |::|||..:..... :..:|||.  |.:|:|.:   |||..::|..
  Fly   470 DVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGG--GKDDVKEIQAHPFFASINWTDLV 532

  Fly   402 IRERPAAIPVEVRSIDDTSNFD-EFPDVSLEIPSAPIPQG--GEIAKDWVFINYTYK 455
            :::.|.....:|.|..||..|| ||...|:|: :.|.|.|  |.||::.:|..::|:
  Fly   533 LKKIPPPFKPQVTSDTDTRYFDKEFTGESVEL-TPPDPTGPLGSIAEEPLFPQFSYQ 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trc	NP_001262071.1	OmpH	16..>85	CDD:214922
trc	NP_001262071.1	STKc_NDR_like	91..455	CDD:270750	124/376 (33%)
Akt1	NP_732113.3	PH_PKB	105..214	CDD:269947
		PH	107..211	CDD:278594
		S_TKc	266..523	CDD:214567	102/308 (33%)
		STKc_PKB	270..590	CDD:270723	121/372 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24356
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010