DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trc and inaC

DIOPT Version :9

Sequence 1:	NP_001262071.1	Gene:	trc / 40165	FlyBaseID:	FBgn0003744	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	NP_476863.1	Gene:	inaC / 36897	FlyBaseID:	FBgn0004784	Length:	700	Species:	Drosophila melanogaster

Alignment Length:	376	Identity:	114/376 - (30%)
Similarity:	185/376 - (49%)	Gaps:	52/376 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 AQLKDESLSEAQRQEKRLQHAQKETEYLRLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHV 118
            |:|:||...:.:..||| :...|:..:...||..:...||..:||||:|:||:|.|.:::.|..:
  Fly   333 ARLRDEVRHDRRPNEKR-RMDNKDMPHNMSKRDMIRAADFNFVKVIGKGSFGKVLLAERRGTDEL 396

  Fly   119 YAMKVLRKADMLEKEQVAHVRAERDVL-VEADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLL 182
            ||:|||||..:::.:.:.....|:.:| :.....::|.|:..||....|:.:||:..|||:|..:
  Fly   397 YAVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHM 461

  Fly   183 MKKDTLSEEGTQFYISETALAIDSIHKLGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRT 247
            .:.....|....||..|.|:|:..:|:...|:||:|.||:|||..||:||.||||
  Fly   462 QQYGRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGL---------- 516

  Fly   248 DFYRDLSQAKPSDFIGTCASLSCSPMDSKRRAESWKRNRRALAYSTVGTPDYIAPEVFLQTGYGP 312
                                       ||...     ..|....:..|||:|:|||:.....|..
  Fly   517 ---------------------------SKEGV-----TERQTTRTFCGTPNYMAPEIVSYDPYSI 549

  Fly   313 ACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKVMNWRETLIFPPEIPISEEAKETIINFCC-EAD 376
            |.||||.||:::|.:.|..||..|:....:|.:.:  :..:||..  .|.||.:.|.:|.. :.:
  Fly   550 AADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKD--KKAVFPKH--FSVEAMDIITSFLTKKPN 610

  Fly   377 RRLGSQR-GLEDLKSVPFFRGVDWEHIRERPAAIPVE--VRSIDDTSNFDE 424
            .|||:.| ..:::.:.||||.|||:.........|::  ::...|.||||:
  Fly   611 NRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDD 661

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trc	NP_001262071.1	OmpH	16..>85	CDD:214922	8/30 (27%)
trc	NP_001262071.1	STKc_NDR_like	91..455	CDD:270750	104/339 (31%)
inaC	NP_476863.1	C1_1	72..124	CDD:278556
		C1_1	137..189	CDD:278556
		C2_PKC_alpha_gamma	194..324	CDD:175992
		S_TKc	371..629	CDD:214567	91/303 (30%)
		STKc_PKC	375..692	CDD:270722	102/333 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24356
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010