DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trc and Pkcdelta

DIOPT Version :9

Sequence 1:	NP_001262071.1	Gene:	trc / 40165	FlyBaseID:	FBgn0003744	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	NP_572797.3	Gene:	Pkcdelta / 32191	FlyBaseID:	FBgn0259680	Length:	1894	Species:	Drosophila melanogaster

Alignment Length:	343	Identity:	115/343 - (33%)
Similarity:	173/343 - (50%)	Gaps:	59/343 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 VEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVL-VEADHQWV 153
            |:||..|.|:|:|:||:|.|.:.:||.:.||:|.|:|..:||.:.|.....||.|| :...|.::
  Fly  1563 VDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYL 1627

  Fly   154 VKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIHKLGFIHRDIK 218
            ..::.:||...:|:.:||:|.|||:|..:.:....|||..:||.:|....:..:||.|.|:||:|
  Fly  1628 CHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYRDLK 1692

  Fly   219 PDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSDFIGTCASLSCSPMDSKRRAESWK 283
            .||:|||..||::::|||:|       :...|.|    |.:|
  Fly  1693 LDNVLLDYEGHVRIADFGMC-------KLQIYLD----KTAD----------------------- 1723

  Fly   284 RNRRALAYSTVGTPDYIAPEVFLQTGYGPACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKVMN- 347
                    |..|||||:|||:.....|....||||.||::||||:|..||...:..:.:..:.|
  Fly  1724 --------SFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNE 1780

  Fly   348 --WRETLIFPPEIPISEEAKETIINFCCEAD--RRLGSQRG-LEDLKSVPFFRGVDWEHIRERPA 407
              |     ||  :.||.|| ..|:....|.|  :|:|||.. ..|:....|||.:||..:.:|..
  Fly  1781 IPW-----FP--VYISAEA-TGILKGLLEKDYTKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQI 1837

  Fly   408 AIPV--EVRSIDDTSNFD 423
            ..|.  :|:...||..||
  Fly  1838 EPPFKPQVKHPLDTQYFD 1855

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trc	NP_001262071.1	OmpH	16..>85	CDD:214922
trc	NP_001262071.1	STKc_NDR_like	91..455	CDD:270750	114/342 (33%)
Pkcdelta	NP_572797.3	S_TKc	1566..1824	CDD:214567	101/307 (33%)
Pkcdelta	NP_572797.3	STKc_nPKC_theta_like	1570..1889	CDD:270744	111/336 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24356
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010