DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment trc and rock2b

DIOPT Version :9

Sequence 1:NP_001262071.1 Gene:trc / 40165 FlyBaseID:FBgn0003744 Length:463 Species:Drosophila melanogaster
Sequence 2:XP_021324031.1 Gene:rock2b / 321070 ZFINID:ZDB-GENE-060125-2 Length:1493 Species:Danio rerio


Alignment Length:449 Identity:169/449 - (37%)
Similarity:246/449 - (54%) Gaps:79/449 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    40 TQYGER-KQRLAKLEAQLKD-------ESLSE------------AQRQEKRLQH--AQKETEYLR 82
            |..|:| :.|:.|||..:|:       |||.:            |.|:.|.:..  ::.|.....
Zfish     3 TGAGKRIESRVRKLETLIKNQKSPLNLESLLDSVTALALDLNHPALRKNKNIDAFLSRYEKAVCN 67

  Fly    83 LKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVE 147
            ||.|::.::||:.:|:|||||||.|:||:.|.:..|||||.|.|.:|:::...|....|||::..
Zfish    68 LKELQVKLDDFDRVKLIGRGAFGAVQLVRHKVSQQVYAMKQLSKFEMVKRSDSAFFWEERDIMAF 132

  Fly   148 ADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIHKLGF 212
            :...|:|::..:|||...|||:|||:||||::||....| :.||..|||.:|..||:|:||.|||
Zfish   133 SQSPWIVQLCCAFQDEKYLYLVMEFMPGGDLVTLTSNYD-IPEEWAQFYTAEVVLALDAIHSLGF 196

  Fly   213 IHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSDFIGTCASLSCSPMDSKR 277
            |||||||||:|||..|||||:|||.|   .|...|...|                  |.      
Zfish   197 IHRDIKPDNMLLDRNGHLKLADFGTC---MKMDSTGMVR------------------CD------ 234

  Fly   278 RAESWKRNRRALAYSTVGTPDYIAPEVFLQTG----YGPACDWWSLGVIMYEMLMGYPPFCSDNP 338
                          :.|||||||:|||.:..|    ||..|||||:||.:||:|:|..||.|::.
Zfish   235 --------------TAVGTPDYISPEVLMSQGGTGYYGRECDWWSVGVFIYELLVGDTPFYSESL 285

  Fly   339 QDTYRKVMNWRETLIFPPEIPISEEAKETIINFCCEADRRLGSQRGLEDLKSVPFFRGVDW--EH 401
            ..||.|:|:.:.:|.||.:|.:|:.||:.|..|....:.||| :.|::::|..|||:...|  :.
Zfish   286 VGTYGKIMDHKNSLTFPDDIEMSKNAKDLICAFLSSREVRLG-RTGVDEIKCHPFFKNDQWTFDT 349

  Fly   402 IRERPAAIPVEVRSIDDTSNF-DEFPDVSLEIPSAPIPQ---GGEIAKDWVFINYTYKR 456
            ||:..|.:..|:.|..||||| |:..|..:...:.|.|:   |.::.    |:.:||.|
Zfish   350 IRDTMAPVVPELSSDIDTSNFDDDIKDDPIGTETFPPPRAFAGNQLP----FVGFTYFR 404

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
trcNP_001262071.1 OmpH 16..>85 CDD:214922 16/66 (24%)
STKc_NDR_like 91..455 CDD:270750 149/373 (40%)
rock2bXP_021324031.1 STKc_ROCK 51..402 CDD:270747 153/397 (39%)
SMC_N <432..1097 CDD:330553
PH_ROCK 1212..1316 CDD:269948
C1 1320..1374 CDD:237996
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D759391at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.920

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