DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trc and Dmpk

DIOPT Version :9

Sequence 1:	NP_001262071.1	Gene:	trc / 40165	FlyBaseID:	FBgn0003744	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	XP_038967160.1	Gene:	Dmpk / 308405	RGDID:	1309825	Length:	646	Species:	Rattus norvegicus

Alignment Length:	392	Identity:	157/392 - (40%)
Similarity:	221/392 - (56%)	Gaps:	65/392 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 RLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLV 146
            |||.:||..:|||.|||||||||.||.:|:.|.||.|||||::.|.|||::.:|:..|.||||||
  Rat    60 RLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLV 124

  Fly   147 EADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMK-KDTLSEEGTQFYISETALAIDSIHKL 210
            :.|.:|:.:::::|||...|||:||:..|||::|||.| .:.:..|..:||::|..:||||:|:|
  Rat   125 KGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHRL 189

  Fly   211 GFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSDFIGTCASLSCSPMDS 275
            |::||||||||:|||..||::|:|||.|..|:..                  ||..||
  Rat   190 GYVHRDIKPDNILLDRCGHIRLADFGSCLKLQPD------------------GTVRSL------- 229

  Fly   276 KRRAESWKRNRRALAYSTVGTPDYIAPEVFLQTG-------YGPACDWWSLGVIMYEMLMGYPPF 333
                            ..||||||::||:....|       |||.||||:|||..|||..|..||
  Rat   230 ----------------VAVGTPDYLSPEILQAVGGGPGAGSYGPECDWWALGVFAYEMFYGQTPF 278

  Fly   334 CSDNPQDTYRKVMNWRETLIFP-PEIPISEEAKETIINFCCEADRRLGSQRGLEDLKSVPFFRGV 397
            .:|:..:||.|::::||.|..| .::.:.|||::.|....|.|:.||| :.|..|.:..|||.|:
  Rat   279 YADSTAETYAKIVHYREHLSLPRADMGVPEEAQDLIRGLLCPAEIRLG-RGGAGDFQKHPFFFGL 342

  Fly   398 DWEHIRERPAAIPVEVRSIDDTSNFDEFPDVSLEIPSAPIPQGGEIAKDW----------VFINY 452
            |||.:|:.......:.....||.|||...|..    :|.:..|||...|.          .|:.|
  Rat   343 DWEGLRDSVPPFTPDFEGATDTCNFDVVEDRL----TAMVSGGGETLSDMQEDMALGVHLPFVGY 403

  Fly   453 TY 454
            :|
  Rat   404 SY 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trc	NP_001262071.1	OmpH	16..>85	CDD:214922	2/2 (100%)
trc	NP_001262071.1	STKc_NDR_like	91..455	CDD:270750	152/383 (40%)
Dmpk	XP_038967160.1	PKc_like	69..406	CDD:419665	152/383 (40%)
Dmpk	XP_038967160.1	DMPK_coil	472..532	CDD:117396
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24356
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020