Protein Alignment trc and Akt3

DIOPT Version :10

• Sequence 1: NP_001262071.1
• Gene: trc / 40165
• FlyBaseID: FBgn0003744
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: XP_038946556.1
• Gene: Akt3 / 29414
• RGDID: 62390
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 433
• Identity: 125/433 - (28%)
• Similarity: 206/433 - (47%)
• Gaps: 85/433 - (19%)

  Fly    10 DGASIRFSD--------HTLDKATKAKVTL-------ENYYSNLVTQYGERKQRLAKLEAQLKDE 59
            ||:.|.:.:        :.|:..:.||..|       .|.:.....|:....:|...::...:.|
  Rat    55 DGSFIGYKEKPQDVDLPYPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEERE 119

  Fly    60 SLSEA--------QRQEKRLQH----------AQKETEYLRLKRLRLGVEDFEALKVIGRGAFGE 106
            ..:||        ||||:...:          .::|.:.......|..:.||:.||::|:|.||:
  Rat   120 EWTEAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGK 184

  Fly   107 VRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVEADHQWVVKMYYSFQDPVNLYLIME 171
            |.||::|.:|..||||:|:|..::.|::|||...|..||....|.::..:.||||....|..:||
  Rat   185 VILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVME 249

  Fly   172 FLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIHKLGFIHRDIKPDNLLLDARGHLKLSDFG 236
            ::.||::...|.::...||:.|:||.:|...|:|.:|....::||:|.:||:||..||:|::|||
  Rat   250 YVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFG 314

  Fly   237 LCTGLKKSHRTDFYRDLSQAKPSDFIGTCASLSCSPMDSKRRAESWKRNRRALAYSTVGTPDYIA 301
            ||    |...||                                      .|...:..|||:|:|
  Rat   315 LC----KEGITD--------------------------------------AATMKTFCGTPEYLA 337

  Fly   302 PEVFLQTGYGPACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKVMNWRETLIFPPEIPISEEAKE 366
            |||.....||.|.|||.|||:||||:.|..||.:.:.:..:..::  .|.:.||.  .:|.:||.
  Rat   338 PEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELIL--MEDIKFPR--TLSSDAKS 398

  Fly   367 TIINFCC-EADRRLGSQRGLEDLKSV---PFFRGVDWEHIRER 405
            .:..... :.::|||.  |.:|.|.:   .||.||:|:.:.::
  Rat   399 LLSGLLIKDPNKRLGG--GPDDAKEIMRHSFFSGVNWQDVYDK 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trc	NP_001262071.1	MobB_Trc-like	24..88	CDD:439274	14/88 (16%)
		STKc_NDR_like	91..455	CDD:270750	106/319 (33%)
Akt3	XP_038946556.1	PH_PKB	4..133	CDD:269947	13/77 (17%)
		Protein Kinases, catalytic domain	175..442	CDD:473864	103/313 (33%)