DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trc and Cdc42bpg

DIOPT Version :9

Sequence 1:	NP_001262071.1	Gene:	trc / 40165	FlyBaseID:	FBgn0003744	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	XP_038964401.1	Gene:	Cdc42bpg / 293693	RGDID:	1307260	Length:	1558	Species:	Rattus norvegicus

Alignment Length:	446	Identity:	170/446 - (38%)
Similarity:	245/446 - (54%)	Gaps:	86/446 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 KQRLAKLEAQLKDES-------------------LSEAQ-RQEKRLQHAQKETEYL--------R 82
            :|||..||..::.|:                   ||.|. |:|:.:      .::|        :
  Rat     2 EQRLRALEQLVRGEAGGSPGLDGLLDLLLGVHQELSSAPLRRERNV------AQFLSWAGPFVTK 60

  Fly    83 LKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVE 147
            :|.|||..:|||.||||||||||||.:|:::|:|.::|||:|.|.:||::.:.|..|.||||||:
  Rat    61 VKELRLQRDDFEILKVIGRGAFGEVAVVRQRDSGQIFAMKMLHKWEMLKRAETACFREERDVLVK 125

  Fly   148 ADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMK-KDTLSEEGTQFYISETALAIDSIHKLG 211
            .|.:||..::|:|||...|||:|::..|||::|||.: :|.|..|..|||::|..|||.|:|:||
  Rat   126 GDSRWVTALHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMVLAIHSLHQLG 190

  Fly   212 FIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSDFIGTCASLSCSPMDSK 276
            ::|||:||||:|||..||::|:|||.|..|..:...|                 :|::
  Rat   191 YVHRDVKPDNILLDMNGHIRLADFGSCLRLNNNGMVD-----------------SSVA------- 231

  Fly   277 RRAESWKRNRRALAYSTVGTPDYIAPEVF--LQTG---YGPACDWWSLGVIMYEMLMGYPPFCSD 336
                             |||||||:||:.  ::.|   |||.||||||||..||:|.|..||.::
  Rat   232 -----------------VGTPDYISPEILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAE 279

  Fly   337 NPQDTYRKVMNWRETLIFPPEI-PISEEAKETIINFCCEADRRLGSQRGLEDLKSVPFFRGVDWE 400
            :..:||.|:||..:.|.||.:: .:...|:..|....|..:.||| :.||:|.:|.|||.|||||
  Rat   280 SLVETYGKIMNHEDHLQFPSDVDDVPASAQALIRQLLCRQEERLG-RGGLDDFRSHPFFEGVDWE 343

  Fly   401 HIRERPAAIPVEVRSIDDTSNFDEFPDVSLEIPSA--PIPQGGEIAKDWVFINYTY 454
            .:....|....|:|...|||||| ..|.:|..|..  |...|........|:.:||
  Rat   344 RLATSTAPYIPELRGPVDTSNFD-VDDDTLNRPETLPPSSHGAFSGHHLPFVGFTY 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trc	NP_001262071.1	OmpH	16..>85	CDD:214922	12/66 (18%)
trc	NP_001262071.1	STKc_NDR_like	91..455	CDD:270750	154/373 (41%)
Cdc42bpg	XP_038964401.1	STKc_DMPK_like	69..399	CDD:270748	154/373 (41%)
		SMC_prok_B	<450..809	CDD:274008
		C1_MRCKgamma	885..936	CDD:410416
		PH_MRCK	944..1076	CDD:269949
		CNH	1103..1366	CDD:395630
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920