Protein Alignment trc and LATS2

DIOPT Version :9

• Sequence 1: NP_001262071.1
• Gene: trc / 40165
• FlyBaseID: FBgn0003744
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_055387.2
• Gene: LATS2 / 26524
• HGNCID: 6515
• Length: 1088
• Species: Homo sapiens
• Alignment Length: 449
• Identity: 198/449 - (44%)
• Similarity: 281/449 - (62%)
• Gaps: 25/449 - (5%)

  Fly    28 KVTLENYYSNLVTQYGERKQRLAKLEAQLKDESLSEAQRQEKRLQHAQKETEYLRLKRLRLGVED 92
            |..:|.:..|::..|.::..|..:||.::....|.||::::.|....|||:.|.||||.::....
Human   603 KFFMEQHVENVIKTYQQKVNRRLQLEQEMAKAGLCEAEQEQMRKILYQKESNYNRLKRAKMDKSM 667

  Fly    93 FEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVEADHQWVVKMY 157
            |..:|.:|.||||||.|..|.||..:||||.|||.|:|.:.|||||:||||:|.|||::||||:|
Human   668 FVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVKLY 732

  Fly   158 YSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIHKLGFIHRDIKPDNL 222
            |||||..:||.:|:::||||||:||::.:...|...:|||:|..|||:|:||:|||||||||||:
Human   733 YSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNI 797

  Fly   223 LLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAK-----PSDFIGTCASLSCSPMDSKRRAESW 282
            |:|..||:||:|||||||.:.:|.:.:|:..|..:     |||.....::..|..........:.
Human   798 LIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRAR 862

  Fly   283 KRNRRALAYSTVGTPDYIAPEVFLQTGYGPACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKVMN 347
            |:::|.||:|.||||:||||||.|:.||...|||||:|||::|||:|.|||.:..|.:|..||:|
Human   863 KQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVIN 927

  Fly   348 WRETLIFPPEIPISEEAKETIINFCCEADRRLGSQRGLEDLKSVPFFRGVDW-EHIRERPAAIPV 411
            |..||..|.::.:|.||::.|...||.||.||| :.|.:|||:.|||..:|: ..||::||....
Human   928 WENTLHIPAQVKLSPEARDLITKLCCSADHRLG-RNGADDLKAHPFFSAIDFSSDIRKQPAPYVP 991

  Fly   412 EVRSIDDTSNFDEFPDVSLEIPSAPIPQGGEIAKDW-------------VFINYTYKRF 457
            .:....||||||   .|..|.|.....:|.  .|.|             .|..:|::||
Human   992 TISHPMDTSNFD---PVDEESPWNDASEGS--TKAWDTLTSPNNKHPEHAFYEFTFRRF 1045

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trc	NP_001262071.1	OmpH	16..>85	CDD:214922	17/56 (30%)
		STKc_NDR_like	91..455	CDD:270750	177/382 (46%)
LATS2	NP_055387.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..49
		UBA_LATS2	101..141	CDD:270581
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	271..323
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	383..428
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	454..483
		PPxY motif	515..518
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	543..592
		STKc_LATS2	666..1046	CDD:173715	179/386 (46%)
		S_TKc	668..973	CDD:214567	156/305 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	994..1022		11/32 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1056..1088

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	1	1.000	-	-		FOG0000273
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920