DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trc and W02B8.2

DIOPT Version :9

Sequence 1:	NP_001262071.1	Gene:	trc / 40165	FlyBaseID:	FBgn0003744	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	NP_496914.1	Gene:	W02B8.2 / 175043	WormBaseID:	WBGene00012198	Length:	1256	Species:	Caenorhabditis elegans

Alignment Length:	278	Identity:	56/278 - (20%)
Similarity:	108/278 - (38%)	Gaps:	93/278 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 MSSRT-------QDADGASIRFSDHTLDKATK-AKVTLENYYSNLVTQYGERKQRLAKLEAQLKD 58
            :|::|       ::....:::.::......|| |:::.||  .||     |||.:..:.|..:||
Worm   157 LSAKTHEIFSIGEELKNKTMKLNEKNSQFQTKLAEISSEN--RNL-----ERKVQKFREELIVKD 214

  Fly    59 ESLSEAQRQEKRLQHAQKET-------EYLRLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTG 116
            :...|..:.::..|...||.       :||..||                   .:|..::::|..
Worm   215 QRSLEVHQDQENTQKVLKEVKQLSDRLDYLTPKR-------------------KDVSRIKERDDF 260

  Fly   117 HVYAMKVLRKADMLEKEQVAHVRAERDVLVEADHQWVVKM----YYSFQDPVNLYLIMEFLPGGD 177
            ..::.|::.  :.:.:.::.:.|.||::   ::.:.:||:    ....|..|...:       ||
Worm   261 LQFSAKIIE--ETMSELKLKNARLEREL---SEKEELVKVTKEELQELQKTVTQAM-------GD 313

  Fly   178 MMTLLMKKDTLSEEGTQFYISETALAIDSIHKLGFIHRDIKPDNLLLDARGHLK----------- 231
                       ||:.|::..:|..       ||.....||:.|  ||:||.:||
Worm   314 -----------SEQATKYLHAENM-------KLTRQKADIRCD--LLEARRNLKGFDEKREELEK 358

  Fly   232 -----LSDFGLCTGLKKS 244
                 |.|....|.|||:
Worm   359 QRDEALEDVRRITELKKN 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trc	NP_001262071.1	OmpH	16..>85	CDD:214922	19/76 (25%)
trc	NP_001262071.1	STKc_NDR_like	91..455	CDD:270750	33/174 (19%)
W02B8.2	NP_496914.1	COG1340	34..305	CDD:224259	31/178 (17%)
		COG1340	351..631	CDD:224259	6/26 (23%)
		DUF4349	<365..497	CDD:305044	5/12 (42%)
		TMPIT	504..>587	CDD:285135
		C1	741..791	CDD:237996
		PH	813..915	CDD:214574
		PH	813..914	CDD:278594
		CNH	941..1222	CDD:214481
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010