DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trc and let-502

DIOPT Version :9

Sequence 1:	NP_001262071.1	Gene:	trc / 40165	FlyBaseID:	FBgn0003744	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	NP_491440.1	Gene:	let-502 / 172088	WormBaseID:	WBGene00002694	Length:	1173	Species:	Caenorhabditis elegans

Alignment Length:	392	Identity:	144/392 - (36%)
Similarity:	216/392 - (55%)	Gaps:	59/392 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 LKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVE 147
            |..||:...||..||||||||||||.||:...|..|||||:|.|.||:::...|....|||::..
Worm    58 LAALRMKAADFRQLKVIGRGAFGEVHLVRHTRTNTVYAMKMLNKDDMIKRADSAFFWEERDIMAH 122

  Fly   148 ADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIHKLGF 212
            |:.:|:|::.|:||||.:||::||::||||::.|:...: :||:.|:||.:|...|:.::|.:|:
Worm   123 ANSEWIVRLQYAFQDPRHLYMVMEYMPGGDLVNLMTSYE-VSEKWTRFYTAEIVEALAALHSMGY 186

  Fly   213 IHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSDFIGTCASLSCSPMDSKR 277
            ||||:||||:|:...||:||:|||.|..:..:                     ..:.||
Worm   187 IHRDVKPDNMLISISGHIKLADFGTCVKMNAN---------------------GVVRCS------ 224

  Fly   278 RAESWKRNRRALAYSTVGTPDYIAPEVFLQTG----YGPACDWWSLGVIMYEMLMGYPPFCSDNP 338
                          :.|||||||:|||....|    :|...||||:||.:||||:|..||.::..
Worm   225 --------------TAVGTPDYISPEVLRNQGQDAEFGKEVDWWSVGVFIYEMLVGETPFYAEAL 275

  Fly   339 QDTYRKVMNWRETLIFPPEIPISEEAKETIINFCCEADRRLGSQRGLEDLKSVPFFRGVDWEHIR 403
            ..||..:||.:.:|.||.|..||.:||:.|..|...|..||| :..::|:::..||...:|....
Worm   276 VSTYTNIMNHKTSLKFPDEPLISTQAKDIIKKFLSAAPDRLG-RNSVDDIRNHKFFVNDEWTFAT 339

  Fly   404 ERPAAIPV--EVRSIDDTSNFDEFP----DVSLEIPSAPIPQGGEIAKDWVFINYTYKR--FEVR 460
            .|.|:.||  .::|.|||::|:|..    |.:.:........|.::.    ||.:||..  ..|:
Worm   340 LREASPPVIPSLKSDDDTTHFEEIETRDRDNAGDFQLPKTFNGNQLP----FIGFTYSNEYSPVK 400

  Fly   461 NL 462
            ||
Worm   401 NL 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trc	NP_001262071.1	OmpH	16..>85	CDD:214922	1/1 (100%)
trc	NP_001262071.1	STKc_NDR_like	91..455	CDD:270750	137/373 (37%)
let-502	NP_491440.1	PKc_like	41..393	CDD:304357	140/381 (37%)
		S_TKc	68..330	CDD:214567	118/304 (39%)
		PH-like	951..1056	CDD:302622
		C1	1060..1112	CDD:197519
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920