DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trc and Dmpk

DIOPT Version :9

Sequence 1:	NP_001262071.1	Gene:	trc / 40165	FlyBaseID:	FBgn0003744	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	XP_006539579.1	Gene:	Dmpk / 13400	MGIID:	94906	Length:	653	Species:	Mus musculus

Alignment Length:	392	Identity:	156/392 - (39%)
Similarity:	221/392 - (56%)	Gaps:	65/392 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 RLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLV 146
            |||.:||..:|||.|||||||||.||.:|:.|.||.|||||::.|.|||::.:|:..|.||||||
Mouse    60 RLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLV 124

  Fly   147 EADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMK-KDTLSEEGTQFYISETALAIDSIHKL 210
            :.|.:|:.:::::|||...|||:||:..|||::|||.| .:.:..|..:||::|..:||||:|:|
Mouse   125 KGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHRL 189

  Fly   211 GFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSDFIGTCASLSCSPMDS 275
            |::||||||||:|||..||::|:|||.|..|               :|...:
Mouse   190 GYVHRDIKPDNILLDRCGHIRLADFGSCLKL---------------QPDGMV------------- 226

  Fly   276 KRRAESWKRNRRALAYSTVGTPDYIAPEVFLQTG-------YGPACDWWSLGVIMYEMLMGYPPF 333
                       |:|.  .||||||::||:....|       |||.||||:|||..|||..|..||
Mouse   227 -----------RSLV--AVGTPDYLSPEILQAVGGGPGAGSYGPECDWWALGVFAYEMFYGQTPF 278

  Fly   334 CSDNPQDTYRKVMNWRETLIFP-PEIPISEEAKETIINFCCEADRRLGSQRGLEDLKSVPFFRGV 397
            .:|:..:||.|::::||.|..| .:..:.|||::.|....|.|:.||| :.|..|.:..|||.|:
Mouse   279 YADSTAETYAKIVHYREHLSLPLADTVVPEEAQDLIRGLLCPAEIRLG-RGGAGDFQKHPFFFGL 342

  Fly   398 DWEHIRERPAAIPVEVRSIDDTSNFDEFPDVSLEIPSAPIPQGGEIAKDW----------VFINY 452
            |||.:|:.......:.....||.|||...|..    :|.:..|||...|.          .|:.|
Mouse   343 DWEGLRDSVPPFTPDFEGATDTCNFDVVEDRL----TAMVSGGGETLSDMQEDMPLGVRLPFVGY 403

  Fly   453 TY 454
            :|
Mouse   404 SY 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trc	NP_001262071.1	OmpH	16..>85	CDD:214922	2/2 (100%)
trc	NP_001262071.1	STKc_NDR_like	91..455	CDD:270750	151/383 (39%)
Dmpk	XP_006539579.1	PKc_like	69..405	CDD:389743	150/381 (39%)
Dmpk	XP_006539579.1	DMPK_coil	472..532	CDD:117396
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24356
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020