DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trc and Cit

DIOPT Version :9

Sequence 1:	NP_001262071.1	Gene:	trc / 40165	FlyBaseID:	FBgn0003744	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	XP_006530193.1	Gene:	Cit / 12704	MGIID:	105313	Length:	2123	Species:	Mus musculus

Alignment Length:	433	Identity:	144/433 - (33%)
Similarity:	228/433 - (52%)	Gaps:	61/433 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 LVTQYG----ERKQRLAKLEAQLKDESLSEAQRQEKRLQHAQKETEYL-RLKRLRLGVEDFEALK 97
            |:||..    .|:..|..|.|..::.|.....:.:......||.::.: .|:.|:....|||...
Mouse    37 LMTQQQMSALSREGMLDALFALFEECSQPALMKMKHVSSFVQKYSDTIAELRELQPSARDFEVRS 101

  Fly    98 VIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVEADHQWVVKMYYSFQD 162
            ::|.|.|.||::|::|.||.|||||:::|..:|.:|||:....||::|..:...|:.::.|:|||
Mouse   102 LVGCGHFAEVQVVREKATGDVYAMKIMKKKALLAQEQVSFFEEERNILSRSTSPWIPQLQYAFQD 166

  Fly   163 PVNLYLIMEFLPGGDMMTLLMK-KDTLSEEGTQFYISETALAIDSIHKLGFIHRDIKPDNLLLDA 226
            ..||||:||:.||||:::||.: :|.|.|...|||::|..||:.|:|::|::||||||:|:|:|.
Mouse   167 KNNLYLVMEYQPGGDLLSLLNRYEDQLDESMIQFYLAELILAVHSVHQMGYVHRDIKPENILIDR 231

  Fly   227 RGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSDFIGTCASLSCSPMDSKRRAESWKRNRRALAY 291
            .||:||.||                           |:.|.::.:.:|:|
Mouse   232 TGHIKLVDF---------------------------GSAAKMNSNKVDAK--------------- 254

  Fly   292 STVGTPDYIAPEVFL------QTGYGPACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKVMNWRE 350
            ..:|||||:||||..      :..||..|||||:||:.|||:.|..||.......|:..:||::.
Mouse   255 LPIGTPDYMAPEVLTVMNEDRRGTYGLDCDWWSVGVVAYEMVYGKTPFTEGTSARTFNNIMNFQR 319

  Fly   351 TLIFPPEIPISEEAKETIINFCCEADRRLGSQRGLEDLKSVPFFRGVDWEHIRERPAAIPVEVRS 415
            .|.||.:..:|.|..:.:.:..|....||    ..|.|...|||...||.:||..|......::|
Mouse   320 FLKFPDDPKVSSELLDLLQSLLCVQKERL----KFEGLCCHPFFARTDWNNIRNSPPPFVPTLKS 380

  Fly   416 IDDTSNFDEFPDVSLEIPSA--PIPQGGEIAKDWVFINYTYKR 456
            .|||||||| |:.:..:.|:  .:...|...::..|:.::|.:
Mouse   381 DDDTSNFDE-PEKNSWVSSSVCQLSPSGFSGEELPFVGFSYSK 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trc	NP_001262071.1	OmpH	16..>85	CDD:214922	11/51 (22%)
trc	NP_001262071.1	STKc_NDR_like	91..455	CDD:270750	131/372 (35%)
Cit	XP_006530193.1	STKc_CRIK	96..421	CDD:270752	131/371 (35%)
		Smc	473..1372	CDD:224117
		C1	1442..1490	CDD:237996
		PH	1523..1642	CDD:214574
		CNH	1687..1983	CDD:214481
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920