DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trc and rock1

DIOPT Version :9

Sequence 1:	NP_001262071.1	Gene:	trc / 40165	FlyBaseID:	FBgn0003744	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	XP_021334267.1	Gene:	rock1 / 100329779	ZFINID:	ZDB-GENE-100712-2	Length:	1375	Species:	Danio rerio

Alignment Length:	437	Identity:	166/437 - (37%)
Similarity:	241/437 - (55%)	Gaps:	77/437 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 RLAKLEAQLKD-----------ESLS--------EAQRQEKRLQHAQK--ETEYLRLKRLRLGVE 91
            |..|::|.|||           :||.        .|.|:.|.:....|  :....:::.||:..|
Zfish    12 RFEKIDAMLKDPKSEVNTDCLLDSLDALVYDLDFPALRKNKSIDDFLKRYKDTISKIRELRMKAE 76

  Fly    92 DFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVEADHQWVVKM 156
            |:|.:|||||||||||:||:.|.|..|||||:|.|.:|:::...|....|||::..|:..|||::
Zfish    77 DYEVVKVIGRGAFGEVQLVRHKATRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSNWVVQL 141

  Fly   157 YYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIHKLGFIHRDIKPDN 221
            :|:|||...||::||::||||::.|:...| :.|:..:||.:|..||:|.||.:||||||:||||
Zfish   142 FYAFQDDRYLYMVMEYMPGGDLVNLMSNYD-VPEKWARFYTAEVVLALDGIHSMGFIHRDVKPDN 205

  Fly   222 LLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSDFIGTCASLSCSPMDSKRRAESWKRNR 286
            :|||..|||||:|||.|..:.|                              |...|.:
Zfish   206 MLLDKSGHLKLADFGTCMKMNK------------------------------DGMVRCD------ 234

  Fly   287 RALAYSTVGTPDYIAPEVFLQTG----YGPACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKVMN 347
                 :.|||||||:|||....|    ||..|||||:||.:||||:|..||.:|:...||.|:||
Zfish   235 -----TAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMN 294

  Fly   348 WRETLIFPPEIPISEEAKETIINFCCEADRRLGSQRGLEDLKSVPFFRGVD--WEHIRERPAAIP 410
            .:..|.||.:..||::||..|..|..:.:.||| :.|::::|...||:...  ||:|||..|.:.
Zfish   295 HKNALTFPEDSDISKDAKSLICAFLTDREVRLG-RNGVDEIKRHGFFKNDQWTWENIRETAAPVV 358

  Fly   411 VEVRSIDDTSNFDEFPDVSLEIPSAPIPQ---GGEIAKDWVFINYTY 454
            .|:....||||||:..:...|..:.|||:   |.::.    |:.:||
Zfish   359 PELSCDTDTSNFDDIEEDRGEEETFPIPKAFVGNQLP----FVGFTY 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trc	NP_001262071.1	OmpH	16..>85	CDD:214922	12/57 (21%)
trc	NP_001262071.1	STKc_NDR_like	91..455	CDD:270750	152/373 (41%)
rock1	XP_021334267.1	STKc_ROCK1	4..408	CDD:270772	166/437 (38%)
		SMC_N	<426..1105	CDD:330553
		PH_ROCK	1124..1230	CDD:269948
		C1	1234..1288	CDD:237996
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920