Protein Alignment Deaf1 and Deaf1

DIOPT Version :10

• Sequence 1: NP_524169.1
• Gene: Deaf1 / 40164
• FlyBaseID: FBgn0013799
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: XP_008758233.1
• Gene: Deaf1 / 83632
• RGDID: 620671
• Length: 570
• Species: Rattus norvegicus
• Alignment Length: 609
• Identity: 166/609 - (27%)
• Similarity: 255/609 - (41%)
• Gaps: 143/609 - (23%)

  Fly    18 AALAEDVVKEEVILESSSHHHHHHHHQLDTKVRMVTSSSNDNSGSGGASGGTSG------AGGGN 76
            ||.|.:...||.:|............:.:.:.|.||:.:...:.||....||..      |....
  Rat    29 AAAAAESEAEEPVLSRDEDSEEDADSEAERETRRVTAVAVMAAESGHMDMGTEALPSPDEAAAAA 93

  Fly    77 GGGGVVSVPVSLPIGSMITGTTFNVITPDQLPPHFKPMLCVDNNGYLSGSTVS------MGNDLK 135
            ....|.:|.|: .:||    :..||.|..           |.|...:||..:|      :|:.|.
  Rat    94 AFAEVTTVTVA-NVGS----SADNVFTTS-----------VANAASISGHVLSGRTALQIGDSLN 142

  Fly   136 T-----IVIQQQQTQPGGGGGGANNAGTNTTATNTIGLNHDGS---------GSNNSHDSLATLE 186
            |     ||:.                 |:.:...|.||....:         |..:....||.
  Rat   143 TEKATLIVVH-----------------TDGSIVETTGLKGPAAPLTPASLCPGPQSPPTPLAP-- 188

  Fly   187 HAAGGASGVGGGGGGTGGGSSGWSENPSTQHNEVFQIRCKTTCAELYRSKLGSGGRGRCVKYKDK 251
                        |...||....|  :||...:|: .:||:.....||:|:|||||||||:|..:.
  Rat   189 ------------GQEKGGTKYNW--DPSVYDSEL-PVRCRNISGTLYKSRLGSGGRGRCIKQGEN 238

  Fly   252 WHTPSEFEHVCGRGSSKDWKRSIKYGGKSLQSLIDEGTLTPHATNCSCTVCCDDEAGESASGPVR 316
            |::|:|||.:.||.|||||||||:|.|:.||.||.:|.|.|||.:|:|..||||   .:.|||||
  Rat   239 WYSPTEFEAMAGRASSKDWKRSIRYAGRPLQCLIQDGILNPHAASCTCAACCDD---MTLSGPVR 300

  Fly   317 LFTPYKRRKRNQTDLDMESGPKRKRNTHH-------SNNNNSNTNNNNTSGSGA-----NNCVDV 369
            ||.||||||:..   ::.:.|.:|.:..:       :....:.|.:...:.|||     .:.|:.
  Rat   301 LFVPYKRRKKEN---ELPTTPVKKDSPKNITLLPATAATTFTVTPSGQITTSGALTFDRASTVEA 362

  Fly   370 TAAVAAATASVVDENNMF----LSEENI-----TSKDEP-WAALNDS----------LDTSTELV 414
            ||.::.:.|    :.::|    :.|..:     ....|| :....||          |.||...:
  Rat   363 TAVISESPA----QGDVFAGATVQEAGVQPPCRVGHPEPHYPGYQDSCQIAPFPEAALPTSHPKI 423

  Fly   415 DQSQMGNTYERETFVVNINDGSSIAVLDTSQ--SMKNIEHVYCTMVKATNDFKRMLNDMKQSFER 477
            ..:.:.......:........:.::.|:.|:  |...:|.:..:::......|.:....||:
  Rat   424 VLTSLPALAVPPSTPTKAVSPTVVSGLEMSEHRSWLYLEEMVNSLLNTAQQLKTLFEQAKQA--- 485

  Fly   478 RIEVLQKERDAAVSAMRVQVHADIDDPNISGSLHGNEIISAKKCANCNREALAECSLCRKTPYCS 542
                 ...|:|||:..|:||.|:..:               :.|.||.|||::||:.|.|..|||
  Rat   486 -----SSCREAAVTQARMQVDAERKE---------------QSCVNCGREAMSECTGCHKVNYCS 530

  Fly   543 EFCQRKDWNAHQVECTRNPQTTTQ 566
            .|||||||..||..|.::...|.|
  Rat   531 TFCQRKDWKDHQHVCGQSASVTVQ 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Deaf1	NP_524169.1	SAND	219..291	CDD:128554	39/71 (55%)
		zf-MYND	521..557	CDD:460312	22/35 (63%)
Deaf1	XP_008758233.1	SAND	206..278	CDD:128554	29/71 (41%)
		zf-MYND	509..545	CDD:460312	9/35 (26%)