DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Deaf1 and samd11

DIOPT Version :9

Sequence 1:	NP_001262069.1	Gene:	Deaf1 / 40164	FlyBaseID:	FBgn0013799	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	XP_009295182.1	Gene:	samd11 / 569122	ZFINID:	ZDB-GENE-060428-2	Length:	874	Species:	Danio rerio

Alignment Length:	347	Identity:	78/347 - (22%)
Similarity:	128/347 - (36%)	Gaps:	119/347 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 QIRCKTTCAELYRSKLGSGGRGRCVKYKDKWHTPSEFEHVCGRGSSKDWKRSIKYGGKSLQSLID 286
            ::.|....|.||.:||..|.:|..:||:.:|.||:||:.|.||.::|||||||::.||||::|:.
Zfish    97 EVECGENKALLYINKLCQGSKGPSIKYRTEWLTPNEFQFVSGRETAKDWKRSIRHKGKSLKTLMS 161

  Fly   287 EGTLTPHATNCSCTVC-----------------------------------CDDEAGESASGPVR 316
            :|.|..|...|.|..|                                   .|.|..|.|||.
Zfish   162 KGILQVHPPICDCPGCRISSPVNRGRLAEKRTIPLPPTRVPKKELASVFSSDDSEGSERASGD-- 224

  Fly   317 LFTPYKRRKRNQTDLDMESGPKRKRNTHHSNNNNSNTNNNNTSGSG---ANNCVDVTAAVAAATA 378
             ....|:.:.|.|.:         |.:..|:.:...:|.::|...|   ..:|.|::.| :|.|.
Zfish   225 -HADIKQEELNFTIM---------RKSRDSDLSTIISNLHHTRQHGMPEGQSCSDLSLA-SAHTD 278

  Fly   379 SVVDENNMFLSEENITSKDEPWAALNDSLDTSTELVDQSQMGNTYERETFVVNINDGSSIAVLDT 443
            .::.:...:                  |.::|:|....|:...:       |:..:.|....|:.
Zfish   279 DILGKRRAY------------------SPNSSSECPSDSKKSRS-------VSPKENSHTPALEP 318

  Fly   444 SQSMKNIEHVYCTMVKATND----------FKRMLNDM--------------------------- 471
            ...|...|| |..|:.|.|:          ..::.|:|
Zfish   319 GSHMTPEEH-YRRMMSALNEHGSYEEQQQRLYQLANNMGIPSHELLHVRQEAMVAVRNPGGMEAH 382

  Fly   472 -----KQSFERRIEVLQKERDA 488
                 ..|.:||.:.|.:.|||
Zfish   383 VPSAGSSSSQRRKQGLPQHRDA 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Deaf1	NP_001262069.1	SAND	219..291	CDD:128554	31/68 (46%)
Deaf1	NP_001262069.1	zf-MYND	521..557	CDD:280009
samd11	XP_009295182.1	SAND	93..165	CDD:279658	31/67 (46%)
		SAM_Samd7,11	734..801	CDD:188978
		SAM	735..791	CDD:197735
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4333
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900