DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Deaf1 and gmeb-2

DIOPT Version :9

Sequence 1:	NP_001262069.1	Gene:	Deaf1 / 40164	FlyBaseID:	FBgn0013799	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	NP_001317728.1	Gene:	gmeb-2 / 181676	WormBaseID:	WBGene00010010	Length:	517	Species:	Caenorhabditis elegans

Alignment Length:	383	Identity:	77/383 - (20%)
Similarity:	129/383 - (33%)	Gaps:	117/383 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   201 GTGGGSSGWSENPSTQHNEVFQIRCKTTCAELYRSKLGS--GGRGRCVKY--KDKWHTPSEFEHV 261
            |..|..:..::..|.....|..::|.|..|::. :||.:  |....|:..  :.::.:|.||...
Worm    62 GGDGNVNVLAKEASVSLPPVITVKCGTLTAKMV-TKLFTCPGIHQNCILIDGETEYISPKEFTVR 125

  Fly   262 CGRGSSKDWKRSIKYGGKSLQSLIDEGTLTPHATNCSCTVCCDDEAGESASGPVRLFTPYKRRKR 326
            ..:...||||.||:.|..:|::|::..:|..|.....|:..|......:...|..  .|..||:.
Worm   126 ANKDKQKDWKGSIRIGKSNLRTLMEMRSLDFHDHPNQCSAKCQSRNYITPKDPTS--DPSGRRRS 188

  Fly   327 NQTDL------------------DMESGPKRKR---------NTHHSNNN-------NSNTNNNN 357
            :.|.|                  .:.:.||::.         .|...|..       :.|..|||
Worm   189 STTKLIPQNMFSHIPSAFPNASTSLFTVPKKETQMPEGQPTLGTLFKNPTFSRFVAISQNMKNNN 253

  Fly   358 TSGSGANNCVDVTAAVAAATASVVDEN--NMF----LSEENITSKDEPWAALNDSLDTSTELVDQ 416
            .|                 |.|...:.  :||    |.||..||.|          |.:|:|:.|
Worm   254 FS-----------------TPSTTTQPPLSMFPTTSLKEETSTSVD----------DVTTQLLQQ 291

  Fly   417 SQM-----------------------GNTYE-------RETFVVNINDGSSIAVLD--------T 443
            .|.                       .|.|:       :|.....||.|....::|        .
Worm   292 HQQQRVASTLFQTIPSAQPSTFWNTTDNRYQGNIEQQPQEMLAEMINAGLGDNIIDMIVNKINNM 356

  Fly   444 SQSMKNI---EHVYCTMVKATNDFKRMLNDMKQSFERRIEVLQKERDAAVSAMRVQVH 498
            .:.:|.|   .:|...|:.:.|......|.|:.....:.|:.::|:....|  :.|||
Worm   357 REKIKGISSCSNVLLKMLCSLNAADTFCNTMQAMESLQAEIAKEEKHLMKS--QPQVH 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Deaf1	NP_001262069.1	SAND	219..291	CDD:128554	20/75 (27%)
Deaf1	NP_001262069.1	zf-MYND	521..557	CDD:280009
gmeb-2	NP_001317728.1	SAND	80..155	CDD:128554	20/75 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I8333
eggNOG	1	0.900	-	-		E1_KOG4333
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900