DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Deaf1 and gmeb-3

DIOPT Version :9

Sequence 1:	NP_001262069.1	Gene:	Deaf1 / 40164	FlyBaseID:	FBgn0013799	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	NP_497762.2	Gene:	gmeb-3 / 175487	WormBaseID:	WBGene00008092	Length:	376	Species:	Caenorhabditis elegans

Alignment Length:	317	Identity:	64/317 - (20%)
Similarity:	116/317 - (36%)	Gaps:	71/317 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   228 TCA--------ELYRSKLGSGGRGRCVKYKDKWHTPSEFEHVCGRGSSKDWKRSIKYGGKSLQSL 284
            ||.        :|:|.   .|.|..|::|:.::.||.:|..:.|:|..||||..|:....||::|
Worm    79 TCGYVKGIMHLKLFRC---PGIRQACIEYESQYLTPKQFTELGGKGRQKDWKACIRVENVSLRTL 140

  Fly   285 IDEGTLTPHATNCSCTVCCDDEAGESASG--PVRLFTPYKRRKRNQTDLDMESGPKRKRNTHHSN 347
            ::..|:..:.....|...|......:::|  ||        .||:..|: :.||......|..|:
Worm   141 LENKTIDFYNHKSICHGQCQSRNYMNSTGRAPV--------NKRHLEDV-LASGDDASEPTEQSS 196

  Fly   348 NNNSN---TNNNNTSGSGANNCVDVTAAVAAATASVVDENNMFLSEE--------NITSKDEP-- 399
            ...|.   ........:|..|       .|....:.|:..:..:.||        ...:.:.|
Worm   197 GQISEEPIKKRGRGRPAGKKN-------KAKLEINFVESEDQLVFEEFFQPAFSTRSPAPERPVC 254

  Fly   400 ------WAAL-NDSLDTSTELVDQSQMGNTYERETFVVNINDGSSIAVLDTSQSM------KNIE 451
                  ::.| ||.:...:::          :|..|:....|......::..||.      :|..
Worm   255 SPAQDIYSCLQNDPMSFWSQI----------KRSGFISQFCDDIIAGAINLKQSAMTQSLNQNSA 309

  Fly   452 HVYCTMVKATNDFKRMLNDMKQSFERRIEVLQKERDAAVSAMRVQVHA-----DIDD 503
            .|......|....|.::|.: ||.||.:...:|:.:......:.|..|     |:|:
Worm   310 FVLTRATFALGIQKPIVNRV-QSIERNVNEQKKQNEMMEDQGKYQEDAQTEADDLDN 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Deaf1	NP_001262069.1	SAND	219..291	CDD:128554	22/70 (31%)
Deaf1	NP_001262069.1	zf-MYND	521..557	CDD:280009
gmeb-3	NP_497762.2	SAND	74..147	CDD:128554	22/70 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I8333
eggNOG	1	0.900	-	-		E1_KOG4333
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900