Protein Alignment cyc and AHRR

DIOPT Version :10

• Sequence 1: NP_524168.2
• Gene: cyc / 40162
• FlyBaseID: FBgn0023094
• Length: 413
• Species: Drosophila melanogaster
• Sequence 2: NP_001364165.1
• Gene: AHRR / 57491
• HGNCID: 346
• Length: 697
• Species: Homo sapiens
• Alignment Length: 315
• Identity: 73/315 - (23%)
• Similarity: 116/315 - (36%)
• Gaps: 104/315 - (33%)

  Fly    18 YDEEKSARTSDENR------KQNHSEIEKRRRDKMNTYINELSSMIPMCFAMQRKLDKLTVLRMA 76
            |...|..|...:.|      |.|.|   ||.||::|..::.|:|::|....:..|||||:|||::
Human     9 YAGRKRRRPLQKQRPAVGAEKSNPS---KRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLS 70

  Fly    77 VQHLR------------------GIRGSGSLHPFNGSDYRPSFLSDQELKMIILQASEGFLFVVG 123
            |.:||                  |....|...|..||    :.|..:    ::|::..||..||.
Human    71 VSYLRVKSFFQVVQEQSSRQPAAGAPSPGDSCPLAGS----AVLEGR----LLLESLNGFALVVS 127

  Fly   124 CDRGRILYVSDSVSSVLNSTQADLLGQSWFDVLHPKDIGKVKEQLSSLEQCPR------------ 176
            .: |.|.|.|.::...|...|.|::.|:.:|.:|..|......||......|:
Human   128 AE-GTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQPPPLETG 191

  Fly   177 -----ERLIDAK---TMLPVKTDVPQSLCRLC--------------------------------P 201
                 .||:.|:   |..|.:.....:.|.:|                                .
Human   192 DDAILGRLLRAQEWGTGTPTEYSAFLTRCFICRVRCLLDSTSGFLTMQFQGKLKFLFGQKKKAPS 256

  Fly   202 GA----RRSFFC-----------RMKLRTASNNQIKEESDTSSSSRSSTKRKSRL 241
            ||    |.|.||           .||:|:|. .:.|..:||::::.:..|..:.|
Human   257 GAMLPPRLSLFCIAAPVLLPSAAEMKMRSAL-LRAKPRADTAATADAKVKATTSL 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cyc	NP_524168.2	bHLH_SF	31..92	CDD:469605	25/84 (30%)
		PAS	111..173	CDD:214512	18/61 (30%)
		PAS_11	311..411	CDD:464214
AHRR	NP_001364165.1	bHLH-PAS_AhRR	26..85	CDD:381441	22/61 (36%)
		PAS	113..176	CDD:214512	18/67 (27%)