Protein Alignment cyc and npas1

DIOPT Version :10

• Sequence 1: NP_524168.2
• Gene: cyc / 40162
• FlyBaseID: FBgn0023094
• Length: 413
• Species: Drosophila melanogaster
• Sequence 2: NP_001315312.1
• Gene: npas1 / 559419
• ZFINID: ZDB-GENE-060503-934
• Length: 770
• Species: Danio rerio
• Alignment Length: 410
• Identity: 100/410 - (24%)
• Similarity: 168/410 - (40%)
• Gaps: 110/410 - (26%)

  Fly    31 RKQNHSEIEKRRRDKMNTYINELSSMIPMCFAMQRKLDKLTVLRMAVQ--HLRGIRGSGSLHPF- 92
            ||:......:.||.|.|....||:.|:|:..|:..:|||.:::|:.:.  |:|.....|. .|:
Zfish    37 RKEKSRNAARSRRGKENFEFFELAKMLPLPGAITSQLDKASIIRLTISYLHMRHFASQGD-PPWS 100

  Fly    93 -------NGSDYR---PSFLSD---QELKMIILQASEGFLFVVGCDRGRILYVSDSVSSVLNSTQ 144
                   |.|..|   .|.::|   |.|...:||:.:||:|||. ..||.||:|::||..|..:|
Zfish   101 PLMEGENNCSKVRRTSHSLVTDIFEQHLGAHLLQSLDGFVFVVS-QEGRFLYISETVSIYLGLSQ 164

  Fly   145 ADLLGQSWFDVLHPKDIGKVKEQLSSLEQCPRERLIDAKTMLPVKTDVPQSLCRLCPGARRSFFC 209
            .:|.|.|.||.:||.|..::.|:|.                                       .
Zfish   165 VELTGSSVFDYIHPADHVEMAERLG---------------------------------------I 190

  Fly   210 RMKLRTASNNQIKEESDTSSSSRSS-------------------------TKRKSRLT------T 243
            |..||..:..|...||.:||:|.||                         .:.||.||      .
Zfish   191 RPHLRAEAGCQTSHESASSSASTSSLAGTPEPAPHSPCSPVRELSERGFFIRMKSTLTKRGLHVK 255

  Fly   244 GHKYRVIQCTGYLK---SWTPIKDEDQDADSDEQTTNLSCLVAIGR-IPPNVRNSTVPASLDNHP 304
            ...|:||..||.::   :..|        .|.........|||:.. :||:..|.   ..:::|
Zfish   256 SSGYKVIHVTGRIRCRPALVP--------SSSRALHRPMGLVALAHTLPPSTLNE---VRMESH- 308

  Fly   305 NIRHVLFISRHSGEGKFLFIDQRATLVIGFLPQEILGTSFYEYFHNEDIAALMESHKMVMQVPEK 369
                 :|:.|.:.:.:..:.:.|.:..:...|.|::|.:.|.:.|.||:..:.:||:.::: ..:
Zfish   309 -----MFVFRVNMDLQVTYCENRISEYMDLSPAEVVGHTCYHFIHAEDLDTVRQSHEDLLR-KGQ 367

  Fly   370 VTTQVYRFRCKDNSYIQLQS 389
            |.|..||:..:...|:.:||
Zfish   368 VVTGYYRWLQRRGGYLWIQS 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cyc	NP_524168.2	bHLH_SF	31..92	CDD:469605	18/62 (29%)
		PAS	111..173	CDD:214512	26/61 (43%)
		PAS_11	311..411	CDD:464214	19/79 (24%)
npas1	NP_001315312.1	bHLH-PAS_NPAS1_PASD5	34..107	CDD:381574	19/70 (27%)
		PAS	130..188	CDD:214512	25/58 (43%)
		PAS_3	320..391	CDD:430001	17/69 (25%)