Protein Alignment cyc and aha-1

DIOPT Version :10

• Sequence 1: NP_524168.2
• Gene: cyc / 40162
• FlyBaseID: FBgn0023094
• Length: 413
• Species: Drosophila melanogaster
• Sequence 2: NP_001251327.1
• Gene: aha-1 / 172889
• WormBaseID: WBGene00000095
• Length: 453
• Species: Caenorhabditis elegans
• Alignment Length: 419
• Identity: 144/419 - (34%)
• Similarity: 219/419 - (52%)
• Gaps: 68/419 - (16%)

  Fly    12 EIEDENYDEEKSARTSD---ENR----KQNHSEIEKRRRDKMNTYINELSSMIPMCFAMQRKLDK 69
            |.||......|.||..|   ||:    ::||||||:|||:||..|||||:.|:|.|.::.||.||
 Worm    19 EDEDMGMPSGKYARMEDEMGENKERFARENHSEIERRRRNKMTHYINELAEMVPQCASLGRKPDK 83

  Fly    70 LTVLRMAVQHLRGIRGSGSLHPFNGSDYRPSFLSDQELKMIILQASEGFLFVVGCDRGRILYVSD 134
            ||:|||||.|::||||..:.   :.:.|:||||:|||||.:||:|:.||||||.|..|::|||:|
 Worm    84 LTILRMAVSHMKGIRGHTAQ---DETSYKPSFLTDQELKHLILEAANGFLFVVCCQTGKVLYVAD 145

  Fly   135 SVSSVLNSTQADLLGQSWFDVLHPKDIGKVKEQLSSLEQCPRE----RLIDAKTMLPVKTDVPQS 195
            |::.|||..|.|.|.::..:::||.|..|:::||     |..|    :::|.|:. .||.:...:
 Worm   146 SITPVLNLKQEDWLQRNLNELIHPDDQDKIRDQL-----CGSEVSVNKVLDLKSG-SVKREGAST 204

  Fly   196 LCRLCPGARRSFFCRMKLRTASNNQIKEESDTSSSSRSSTKRKSRLTTGHKYRVIQCTGYLKSWT 260
              |:....||.|.|||::           .......|...:|......|..|.|:.||||:|:..
 Worm   205 --RVHMSCRRGFICRMRV-----------GALEPLHRLRNRRPLFQHAGQNYVVMHCTGYIKNAP 256

  Fly   261 PIKDEDQDADSDEQTTNL---SCLVAIGRIPPNVRNSTVPASLDNHPNIRHVLFISRHSGEGKFL 322
            |            |..|.   ||||||.|:    :.:::|...|  |...: .|..|.|.:||..
 Worm   257 P------------QGINAPASSCLVAIARL----QVASMPVCAD--PTSTN-QFSVRVSEDGKMT 302

  Fly   323 FIDQRATLVIGFLPQEILGTSFYEYFHNEDIAALMESHKMV-----MQVPEKVTTQVYRFRCKDN 382
            |||.|.:.:||....:::|..::...|..|...|.:|...:     |::..:|.|......|..:
 Worm   303 FIDARVSDLIGLSSDQLIGRYWWNLAHPADEKTLQDSFVALLSDQPMRINIRVRTSTDYIPCTVS 367

  Fly   383 SYIQLQSEWRAFKNPWTSEIDYIIAKNSV 411
            :|        .|.||::.:.:|::|.:.:
 Worm   368 AY--------KFMNPYSEQFEYVVATHQI 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cyc	NP_524168.2	bHLH_SF	31..92	CDD:469605	35/64 (55%)
		PAS	111..173	CDD:214512	28/61 (46%)
		PAS_11	311..411	CDD:464214	26/104 (25%)
aha-1	NP_001251327.1	bHLH-PAS_ARNT	41..105	CDD:381517	35/66 (53%)
		PAS	120..179	CDD:214512	26/58 (45%)
		PAS_11	288..393	CDD:464214	26/110 (24%)