DRSC/TRiP Functional Genomics Resources

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Protein Alignment cyc and tgo

DIOPT Version :10

Sequence 1:NP_524168.2 Gene:cyc / 40162 FlyBaseID:FBgn0023094 Length:413 Species:Drosophila melanogaster
Sequence 2:XP_061516546.1 Gene:tgo / 1279156 VectorBaseID:AGAMI1_006771 Length:882 Species:Anopheles gambiae


Alignment Length:408 Identity:180/408 - (44%)
Similarity:256/408 - (62%) Gaps:35/408 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 EDENYDEEKSARTSDENRKQNHSEIEKRRRDKMNTYINELSSMIPMCFAMQRKLDKLTVLRMAVQ 78
            ||...|:|:.|      .::||.|||:|||:||..||.|||.|:|.|.|:.||.||||:|||||.
Mosquito   155 EDNVQDKERFA------SRENHCEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVA 213

  Fly    79 HLRGIRGSGSLHPFNGSDYRPSFLSDQELKMIILQASEGFLFVVGCDRGRILYVSDSVSSVLNST 143
            |::.:||:|:.:. :|| |:||||:|||||.:||:|::|||||.|||.|||:||||||:.|||.:
Mosquito   214 HMKALRGTGNTNT-DGS-YKPSFLTDQELKHLILEAADGFLFVAGCDTGRIIYVSDSVTPVLNYS 276

  Fly   144 QADLLGQSWFDVLHPKDIGKVKEQLSSLEQCPRERLIDAKTMLPVKTDVPQSLCRLCPGARRSFF 208
            |.:....|.||.:||.||.||:||||:.|.....|::|.||. .||.:..||..|||.|:||.|.
Mosquito   277 QNEWYSGSLFDHIHPDDIEKVREQLSTQEPVNSGRILDLKTG-TVKKEGHQSSMRLCMGSRRGFI 340

  Fly   209 CRMKLRTASNNQIKEESDTSSSSRSSTKRKSRL---TTGHKYRVIQCTGYLKSWTPIK------- 263
            |||::     ..:..|| .:....:..:||:.|   |.||.|.|:.||||:|:|.|..       
Mosquito   341 CRMRI-----GPLTPES-MALGHLNRLRRKNSLGPSTDGHSYAVMHCTGYIKNWPPTDMFPGVTI 399

  Fly   264 DEDQDADSDEQTTNLSCLVAIGRIPPNVRNSTVPASLD-NHPNIRHVLFISRHSGEGKFLFIDQR 327
            |..||   ||......|||||.|:  .:.:||....|. |:||    .|||||:..|||.|:|||
Mosquito   400 DRGQD---DELHNTHCCLVAIARL--QITSSTTANDLSANNPN----EFISRHAMCGKFTFVDQR 455

  Fly   328 ATLVIGFLPQEILGTSFYEYFHNEDIAALMESHKMVMQVPEKVTTQVYRFRCKDNSYIQLQSEWR 392
            ...|:|:.|.::|..|.|::||.:|||.:.|:...|::...::.:.:||||.|:..::.::::..
Mosquito   456 VIGVLGYQPVDLLNKSCYDFFHPDDIAHMKENFDQVLKQKGQMFSVMYRFRAKNKEWVWMRTQAY 520

  Fly   393 AFKNPWTSEIDYIIAKNS 410
            ||.||:|.:|:|::..||
Mosquito   521 AFLNPYTDDIEYVVCTNS 538

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cycNP_524168.2 bHLH_SF 31..92 CDD:469605 34/60 (57%)
PAS 111..173 CDD:214512 37/61 (61%)
PAS_11 311..411 CDD:464214 39/100 (39%)
tgoXP_061516546.1 None

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