Protein Alignment Cyp305a1 and DIT2

DIOPT Version :10

• Sequence 1: NP_649151.1
• Gene: Cyp305a1 / 40161
• FlyBaseID: FBgn0036910
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_010690.1
• Gene: DIT2 / 852011
• SGDID: S000002810
• Length: 489
• Species: Saccharomyces cerevisiae
• Alignment Length: 578
• Identity: 122/578 - (21%)
• Similarity: 188/578 - (32%)
• Gaps: 173/578 - (29%)

  Fly     1 MSALIFLCAIL---IGFVIYSLI-SSARRPKNFPPGPRFVPWLG----------NTLQFRKEASA 51
            |..|..||.||   :.:|.:::| .....|||.|..|.:|.:|.          ..|..|:....
Yeast     1 MELLKLLCLILFLTLSYVAFAIIVPPLNFPKNIPTIPFYVVFLPVIFPIDQTELYDLYIRESMEK 65

  Fly    52 VGGQHILF-ERW----------AKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNF 105
            .|.....| .||          |:.|:.:....|.|.:           |::....:.....||
Yeast    66 YGAVKFFFGSRWNILVSRSEYLAQIFKDEDTFAKSGNQ-----------KKIPYSALAAYTGDN- 118

  Fly   106 FLRLRTMGTRKGITCTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPI 170
                        :....|.:|..:|:                         .:...|:..::.||
Yeast   119 ------------VISAYGAVWRNYRN-------------------------AVTNGLQHFDDAPI 146

  Fly   171 EPVTWLAQSVLNVLWCLIAGKRIARQED---GTL--RRLLDLMNRRSKLFDICGGLLAQ------ 224
                   .....:|..||..:.:..|..   |.|  |..||.:::.:..||. |.|..:
Yeast   147 -------FKNAKILCTLIKNRLLEGQTSIPMGPLSQRMALDNISQVALGFDF-GALTHEKNAFHE 203

  Fly   225 ----------------FPWLRHVAP---------DRTGYN--LIQQLNTEL---YGFFMDTIEEH 259
                            ||:| .|.|         |...:.  |::::..||   |.|...|.
Yeast   204 HLIRIKKQIFHPFFLTFPFL-DVLPIPSRKKAFKDVVSFRELLVKRVQDELVNNYKFEQTTF--- 264

  Fly   260 RRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVMTILDFFIAGSQTTSNTINLALMV 324
                      |.||||.|:..|:.|..           ||...|:...:||.:......|.:|.:
Yeast   265 ----------AASDLIRAHNNEIIDYK-----------QLTDNIVIILVAGHENPQLLFNSSLYL 308

  Fly   325 LA-MRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWA 388
            || ...:.||||..:|............|         .::||:.||.|.:........|.....
Yeast   309 LAKYSNEWQEKLRKEVNGITDPKGLADLP---------LLNAFLFEVVRMYPPLSTIINRCTTKT 364

  Fly   389 TKLGG-YDIPKNATILISLRSVHLDKEHWKDPL-EFRPERFIDSAGKCFKDEYFMP--------F 443
            .|||. ..|||...:..:......|.:.|.... :|:|||: .|..:..:..:.|.        |
Yeast   365 CKLGAEIVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPERW-GSDIETIRKNWRMAKNRCAVTGF 428

  Fly   444 GMGRRRCLGDALARACIFSFLVRIVQHFSVVL-PAGESPSMVLLPGITLTPKPYKVQF 500
            ..|||.|||:.||...:...|..:::.|...| |..|..   |.|...|.|...|::|
Yeast   429 HGGRRACLGEKLALTEMRISLAEMLKQFRWSLDPEWEEK---LTPAGPLCPLNLKLKF 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	CYP15A1-like	68..498	CDD:410744	97/482 (20%)
DIT2	NP_010690.1	CYP56-like	65..485	CDD:410693	105/514 (20%)