DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP78A10

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_177551.1	Gene:	CYP78A10 / 843751	AraportID:	AT1G74110	Length:	537	Species:	Arabidopsis thaliana

Alignment Length:	481	Identity:	105/481 - (21%)
Similarity:	192/481 - (39%)	Gaps:	74/481 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 PGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRSD-LVGLKLGREYVVVALGHEMVKEVQL 94
            |||..:|..|..|.|...|..    |.:....|...::. |:...:|....|:....|..||:..
plant    65 PGPSGLPIFGLLLAFVNNALT----HRILANIADTCKAKALMAFSVGSTRFVITSEPETAKELLN 125

  Fly    95 QEVFEGRP--DNFFLRL--RTMGTRKGITCTDGQLWYEHRH------FAMKQMRNVGYGRSQMEH 149
            ...|..||  ::.:..|  |.||     ....|..|.|.|.      |:.|::.:.|..|.::..
plant   126 SSAFADRPVKESAYELLFDRAMG-----FAPFGDYWRELRRISSTHLFSPKRIFSSGESRRKIGQ 185

  Fly   150 HIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAGKR-------IARQEDGTLRRLLDL 207
            ::   ..|:...:|...|..|:.:  |....||.:...:.||.       :..:|...|..|:
plant   186 NM---VGEIKNAMECYGEVHIKKI--LHFGSLNNVMSSVFGKTYNFNEGIVYSKESNELEHLV-- 243

  Fly   208 MNRRSKLFDICG--GLLAQFP---WLRHVAPDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDP 267
                |:.:::.|  .....||   ||......|...:|:.::|.    |....|.:|:.:.:...
plant   244 ----SEGYELLGIFNWSDHFPGMRWLDLQGVRRRCRSLVGRVNV----FVGKIINDHKSKRSLRD 300

  Fly   268 SPAESDLIYAYLQEMKDRSAGGE-SSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDV 331
            :|.||    .|..:..|...|.. :|..:::.::..:.:....|:.|.:..:...|..:.:.||:
plant   301 NPEES----TYDDDFVDVLLGMHGNSKLSDSDMIAVLWEMIFRGTDTVAILLEWILARMVLHPDI 361

  Fly   332 QEKLFSQVTASVAAASTDAFPHLSRREAFD-------YMDAFIMEVQRFFHITP-ITGPRRALWA 388
            |.|         |.|..|.....|.|:..|       |:.|.:.|..|.....| ::..|.::..
plant   362 QAK---------AQAEIDCIVGDSGRQVTDSDLPKLPYVRAIVKETLRMHPPGPLLSWARLSIHD 417

  Fly   389 TKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGK-----CFKDEYFMPFGMGRR 448
            |::|.:.||...|.::::.::..|::.|.:..|::||||:.:...     ...|....|||.|||
plant   418 TQIGTHFIPAGTTAMVNMWAITHDEKVWPEAHEYKPERFLGAQESNNFPIMGSDLRLAPFGAGRR 482

  Fly   449 RCLGDALARACIFSFLVRIVQHFSVV 474
            .|.|.::..|.:..:|.:::..:..|
plant   483 VCPGKSMGLATVELWLAQLLGSYKWV 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	105/481 (22%)
CYP78A10	NP_177551.1	CYP78	97..529	CDD:410699	95/445 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000