DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp305a1 and CYP89A2

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_176670.1	Gene:	CYP89A2 / 842798	AraportID:	AT1G64900	Length:	506	Species:	Arabidopsis thaliana

Alignment Length:	536	Identity:	126/536 - (23%)
Similarity:	212/536 - (39%)	Gaps:	131/536 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSALIFLCAILIGFVIYSLISSARRPKN--FPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWA 63
            |...:.:.|.|.|.::..|:...|...:  .||.|.|:|:|| |||:.:|  .:||    .|.:.
plant     1 MEIWLLILASLSGSLLLHLLLRRRNSSSPPLPPDPNFLPFLG-TLQWLRE--GLGG----LESYL 58

  Fly    64 KDFR---SDLVGLKL-GREYVVVA---LGHEMVKEVQLQEVFEGRP---------DNFFLRLRTM 112
            :...   ..:|.|:: .|..:.||   |.||.:  |....|:..||         |...:...:.
plant    59 RSVHHRLGPIVTLRITSRPAIFVADRSLTHEAL--VLNGAVYADRPPPAVISKIVDEHNISSGSY 121

  Fly   113 GT-----RKGITCTDGQLW-------YEH-RHFAM----KQMRNVGYGRSQ--MEHHIELEAEEL 158
            |.     |:.||   .::.       |.| ||:.:    ::.||.| |...  :.||:......|
plant   122 GATWRLLRRNIT---SEILHPSRVRSYSHARHWVLEILFERFRNHG-GEEPIVLIHHLHYAMFAL 182

  Fly   159 LGQL---ERTEEQPIEPVTWLAQ---------SVLNVLW----CLIAGKR------IARQEDGTL 201
            |..:   ::.:|:.|:.|.::.:         ::.|: |    .||..||      |.||:...
plant   183 LVLMCFGDKLDEKQIKEVEFIQRLQLLSLTKFNIFNI-WPKFTKLILRKRWQEFLQIRRQQRDV- 245

  Fly   202 RRLLDLMNRRSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKD 266
              ||.|:..|.|:                                         :||.:|...:|
plant   246 --LLPLIRARRKI-----------------------------------------VEERKRSEQED 267

  Fly   267 PSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDV 331
                :.|.:.:|:..:.|.....|:...||..::....:|..||:.||:..:...:..|...|::
plant   268 ----KKDYVQSYVDTLLDLELPEENRKLNEEDIMNLCSEFLTAGTDTTATALQWIMANLVKYPEI 328

  Fly   332 QEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDI 396
            ||:|..::.:.|...:.:.  .....|...|:.|.::|..|.........|......|.||||.:
plant   329 QERLHEEIKSVVGEEAKEV--EEEDVEKMPYLKAVVLEGLRRHPPGHFLLPHSVTEDTVLGGYKV 391

  Fly   397 PKNATILISLRSVHLDKEHWKDPLEFRPERF------IDSAGKCFKDEYFMPFGMGRRRCLGDAL 455
            |||.||...:..:..|...|::|:.|:||||      :|..|.  :....||||.|||.|.|..|
plant   392 PKNGTINFMVAEIGRDPVEWEEPMAFKPERFMGEEEAVDLTGS--RGIKMMPFGAGRRICPGIGL 454

  Fly   456 ARACIFSFLVRIVQHF 471
            |...:..::..:|:.|
plant   455 AMLHLEYYVANMVREF 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	120/505 (24%)
CYP89A2	NP_176670.1	CYP77_89	64..497	CDD:410698	106/466 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000