DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP705A25

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_175471.1	Gene:	CYP705A25 / 841477	AraportID:	AT1G50560	Length:	519	Species:	Arabidopsis thaliana

Alignment Length:	532	Identity:	127/532 - (23%)
Similarity:	221/532 - (41%)	Gaps:	88/532 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LCAILIGFVIYSLISSA----RRPKN-------FPPGPRFVPWLGNTLQFRKEASAVGGQHILFE 60
            ||.|.|...|:||...:    ::||:       .||.|..:|.:|: |.|           :|..
plant    10 LCFIFILLAIFSLFCFSAFFFKKPKDPQLQGCGLPPSPPSLPIIGH-LHF-----------LLSV 62

  Fly    61 RWAKDFRSDLVGLKLGREY------------VVVALGHEMVKEV-QLQEV-FEGRPDN---FFLR 108
            ...|.|:      ||..:|            :|:.....|..|| ::|:: |..|...   ...:
plant    63 PCYKSFQ------KLSSKYGPFLHLRAFNIPIVLVSSGSMANEVLRIQDLNFASRDSGQTPIMEK 121

  Fly   109 LRTMGTRKGITCTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEEL----LGQLERTEEQP 169
            ....|:...::...|..|...:...:|::    .|...:|....|..:||    ....::..:..
plant   122 SLLFGSFGFVSVPYGDYWRFMKKLLVKKL----LGSHSLEQTRLLRGKELQTFRAMLFDKAAKNE 182

  Fly   170 IEPVTWLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRR---SKLFDICGGLLAQFPWLRHV 231
            ...|......:.|...|.:...|...:|:|...::..|:.:.   :|.| :...::.||..|
plant   183 TVDVGKEMMKLTNNSICRMTMGRSCSEENGEAEQVRGLVTKSLSLTKKF-LIASIVGQFSKL--- 243

  Fly   232 APDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAES-DLIYAYLQEMKDRSAGGESSTFN 295
                .|.:|..:...|:...:.:.:|:..::..::|:..|. |::...|:...|.:|   ....:
plant   244 ----VGISLFGKEIMEVSQRYDELLEKIIKEHEENPNNGEDRDMMDVLLEVCADDNA---EFKIS 301

  Fly   296 ETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAA----ASTDAFPHLSR 356
            ..|:....::.|:||:.|::.||...|..|...|::.|||..::.:.|..    ..|| .|:|
plant   302 RNQIKALFVEIFLAGTDTSAQTIQWILAELINHPEILEKLRKEIESVVGVRRLIQETD-LPNL-- 363

  Fly   357 REAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLE 421
                .|:.|.:.|..|....|||. .|.|....|:|||.|.:|.|::::..:|..|.:.|:.|.|
plant   364 ----PYLQAVMKEGLRLHPHTPIL-VRNATEGCKIGGYYIGQNTTMMVNAYAVLRDPDSWEYPEE 423

  Fly   422 FRPERFIDSAGKCFKDE------YFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGES 480
            |:||||:.|..|..:||      .|:|||.|||.|||..|....:...:..:||.|...: .|:.
plant   424 FQPERFMTSPLKGKEDEKAQLALNFIPFGSGRRGCLGKNLGYIFMGVAIGTMVQGFDWRI-NGDK 487

  Fly   481 PSMVLLPGITLT 492
            .:|.....:|||
plant   488 VNMEETGEMTLT 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	118/498 (24%)
CYP705A25	NP_175471.1	p450	54..517	CDD:299894	114/488 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000