DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP76C6

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_174633.1	Gene:	CYP76C6 / 840263	AraportID:	AT1G33720	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	534	Identity:	124/534 - (23%)
Similarity:	202/534 - (37%)	Gaps:	125/534 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LIFLCAILIGFVIYSLISSARRP---KNFPPGPRFVPWLGNTLQFRKEASAVG-GQHILFERWAK 64
            ||| |.||...:.::...|.|.|   ...||||..:|.:||       ...|| ..|..|...:|
plant    11 LIF-CFILSCLLFFTTARSRRSPCQLSKSPPGPPRLPIIGN-------IHLVGKNPHHSFTDLSK 67

  Fly    65 DFRSDLVGLKLGREYVVVALGHEMVKEV--QLQEVFEGR--------------------PDNFFL 107
            .: ..::.||||....||....:.|:||  ...::..||                    |.:...
plant    68 TY-GPVMSLKLGCLNSVVIASRDAVREVLKTHDQILSGRYISEATKSNNHHEFSVGWIHPSSSRF 131

  Fly   108 RLRTMGTRKGITCTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQL----ERTEEQ 168
            |:    .|| ::.|  ||:......|.|.:|        |:     :.:||:..|    ||.|..
plant   132 RM----LRK-LSAT--QLFSPQCIQATKALR--------MK-----KVQELVNFLSESCEREEAV 176

  Fly   169 PIEPVTWLA--QSVLNVLWCLIAGKRIARQEDG---------------------TLRRLLDLMNR 210
            .|..|:::.  ..:.|:|:.:..|...::....                     ...|.|||...
plant   177 DISHVSFVTALNIISNILFSVNLGSYDSKNSSAFQEMVIGYQESIGNPDLANFFPFMRFLDLQGN 241

  Fly   211 RSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLNTELYGFFMDT--IEEHRRQLAKDPSPAESD 273
            ..|:.:..|.||                        :::..|.|.  :|:..|.:.||.|..:
plant   242 SKKMRESSGRLL------------------------QVFREFYDARIVEKSSRSVEKDVSSKD-- 280

  Fly   274 LIYAYLQEMKDRSAGGESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQ 338
                :|..:.|...|.|:. .|..::...:||.|:||:.|.|:|:..|:..|...|....|:..:
plant   281 ----FLDVLIDLQQGDETE-INIDEIEHLLLDMFVAGTDTNSSTVEWAMAELLGNPKTMTKVQDE 340

  Fly   339 VTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATIL 403
            :...:..........:|:   ..|:.|.:.|..|.....|....|:|....::.|:.:.|::.:|
plant   341 INHVIGQNGDFQESDISK---LPYLKAVVKETFRLHPAAPFLLQRKAETNVEILGFTVLKDSQVL 402

  Fly   404 ISLRSVHLDKEHWKDPLEFRPERF----IDSAGKCFKDEYFMPFGMGRRRCLGDALARACIFSFL 464
            :::.::..|...|::|..|.||||    ||..|   .|....|||.|||.|.|..||...:...|
plant   403 VNVWAIGRDPLVWENPTHFEPERFLGKEIDVKG---TDYELTPFGAGRRICPGLPLAMKTVHLML 464

  Fly   465 VRIVQHFSVVLPAG 478
            ..::..|...||.|
plant   465 ASLLYTFEWKLPNG 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	115/505 (23%)
CYP76C6	NP_174633.1	p450	11..504	CDD:299894	124/534 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000