DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP78A8

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_171627.2	Gene:	CYP78A8 / 839233	AraportID:	AT1G01190	Length:	540	Species:	Arabidopsis thaliana

Alignment Length:	495	Identity:	117/495 - (23%)
Similarity:	188/495 - (37%)	Gaps:	95/495 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 RRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAK----DFRSDLVGLKLGREYVVVAL 84
            |:.||..||||..|.:|        :.::...|:..:|.|.    .....|:...||...|||..
plant    73 RKYKNLIPGPRGFPLVG--------SMSLRSSHVAHQRIASVAEMSNAKRLMAFSLGDTKVVVTC 129

  Fly    85 GHEMVKEVQLQEVFEGRP-DNFFLRL---RTMGTRKGITCTDGQLWYEHRH------FAMKQMRN 139
            ...:.||:....||..|| |.....|   |.||     ...:|..|...|.      |..||::
plant   130 HPAVAKEILNSSVFADRPVDETAYGLMFNRAMG-----FAPNGTYWRTLRRLGSNHLFNPKQIK- 188

  Fly   140 VGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAGKRIARQEDGTLRRL 204
                  |.|....:.|.:::....|..:........|..:.|..:..|:.|:....:.:..|..
plant   189 ------QSEDQRRVIATQMVNAFARNPKSACAVRDLLKTASLCNMMGLVFGREYELESNNNLES- 246

  Fly   205 LDLMNRRSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLN-TE----LYGFFMDTIEEHRRQLA 264
                       :...||:.:            ||:|:..|| |:    |.|.....|.....||.
plant   247 -----------ECLKGLVEE------------GYDLLGTLNWTDHLPWLAGLDFQQIRFRCSQLV 288

  Fly   265 KDPSPAESDLIYAYLQEMKDRSAGGE----------SSTFNETQLVMTILDFFIAGSQTTSNTIN 319
            ...:...|.:|:      :.|:|.|.          |...:|:.:|..:.:....|:.|.:..:.
plant   289 PKVNLLLSRIIH------EQRAATGNFLDMLLSLQGSEKLSESDMVAVLWEMIFRGTDTVAVLVE 347

  Fly   320 LALMVLAMRPDVQEKLFSQVTASVAAAST---DAFPHLSRREAFDYMDAFIMEVQRFFHITP-IT 380
            ..|..:.|.|.||..:..::...|..:.|   ...|.|:      |:.|.|.||.|.....| ::
plant   348 WVLARIVMHPKVQLTVHDELDRVVGRSRTVDESDLPSLT------YLTAMIKEVLRLHPPGPLLS 406

  Fly   381 GPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKC-----FKDEYF 440
            ..|.::..|.:.||.:|...|.::::.::..|...|:|||||:||||:...|:.     ..|...
plant   407 WARLSITDTSVDGYHVPAGTTAMVNMWAIARDPHVWEDPLEFKPERFVAKEGEAEFSVFGSDLRL 471

  Fly   441 MPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGES 480
            .|||.|:|.|.|..|....: ||.|..:.|....||:.|:
plant   472 APFGSGKRVCPGKNLGLTTV-SFWVATLLHEFEWLPSVEA 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	114/489 (23%)
CYP78A8	NP_171627.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000