DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP71B10

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_200536.3	Gene:	CYP71B10 / 835831	AraportID:	AT5G57260	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	523	Identity:	124/523 - (23%)
Similarity:	222/523 - (42%)	Gaps:	97/523 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSALIFLCAI-LIGFVIYSLISSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQ--HILFERW 62
            |:.|.|:..| ||..::.::..|.||....||.|..:|.:||..|.        |:  |....:.
plant     1 MTVLWFVSLILLISILLVAVKHSKRRWVRQPPSPPGLPIIGNLHQL--------GELPHQSLCKL 57

  Fly    63 AKDFRSDLVGLKLGREYVVVALGHEMVKEV----------------------QLQEVFEGRPDNF 105
            :|.: ..::.|||||...|:....|..|:|                      ...::...|.|::
plant    58 SKKY-GPVMLLKLGRVPTVIVSTPETAKQVLKDYDLHCCSRPSLEGTRKLSYNYLDIAFSRFDDY 121

  Fly   106 FLRLRTMGTRKGITCTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQL-ERTEEQP 169
            :..||.:       |.: :|:...|..:::.::             |.|.|:|:..: |...::.
plant   122 WKELRKL-------CVE-ELFCNKRINSIQPIK-------------EAEMEKLIDSIAESASQKT 165

  Fly   170 IEPV--TWLAQSVLNVLWCLIAGKRIARQEDGTL---RRLLDLMNRRSKLFDICGGLLAQ--FPW 227
            :..:  |:|:.:| ||:...:.|...    .||:   .:..||::   :..::.|...|.  ||:
plant   166 LVNLSDTFLSLNV-NVICKAVFGVNF----QGTVLNNDKFQDLVH---EALEMLGSFSASDFFPY 222

  Fly   228 LRHVAPDRTGYNLIQQLNT-ELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGES 291
            :..:....||.:..::.:. :|..|:...|:.|   |.|:...:|.|.:...|:..|:.:..|..
plant   223 VGWIVDWFTGLHARRERSVRDLDAFYEQMIDLH---LQKNREESEDDFVDLLLRLEKEEAVLGYG 284

  Fly   292 S-TFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVA------AASTD 349
            . |.|..:.:  :::..:.|..|::.|:..|:..|...|.|.:|:.|::.|.:.      ..|.|
plant   285 KLTRNHIKAI--LMNILLGGINTSAITMTWAMAELIRNPRVMKKVQSEIRAQIGKNNKTRIISLD 347

  Fly   350 AFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKE 414
            ...|||      |::..|.|..|...:.|:..||..:...|:.||.|.....:.:::.::..|.|
plant   348 EINHLS------YLNMVIKETCRLHPVAPLLVPREVISEFKINGYTIQPKTRLHVNVWAIGRDPE 406

  Fly   415 HWKDPLEFRPERF----IDSAGKCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVL 475
            .||||.||.||||    ||..|   :|...:|||.|||.|....:....:...|..::.||...|
plant   407 IWKDPEEFLPERFMDCDIDVKG---QDYELLPFGSGRRICPAVYMGITTVEFGLANLLYHFDWKL 468

  Fly   476 PAG 478
            |.|
plant   469 PEG 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	115/493 (23%)
CYP71B10	NP_200536.3	CYP71-like	60..493	CDD:410695	105/456 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000