DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP705A5

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_199610.1	Gene:	CYP705A5 / 834850	AraportID:	AT5G47990	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	545	Identity:	125/545 - (22%)
Similarity:	222/545 - (40%)	Gaps:	100/545 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SALIFLCAILIGFVIYSLISSARRPKN------FPPGPRFVPWLGNTLQFRKEASAVGGQH-ILF 59
            :..|||...|...:.|.|.  .|:.|:      .||.|..:|.:|:.             | |||
plant    11 NCFIFLLLCLFSRLSYDLF--FRKTKDSRAGCALPPSPPSLPIIGHL-------------HLILF 60

  Fly    60 ERWAKDFRS------DLVGLKLGREYVVVALGHEMVKEV-QLQEV-FEGRPDNFFLRLRTMGTRK 116
            ....:.|::      .|:.|:.....:|:........|: :.|:| ...||.........:|:..
plant    61 VPIHQSFKNISSKYGPLLHLRFFNFPIVLVSSASTAYEIFKAQDVNVSSRPPPPIEESLILGSSS 125

  Fly   117 GITCTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLER---------TEEQPIEP 172
            .|....|    ::..|..|.|.....|...::....:.|:|    |||         .::|.:|
plant   126 FINTPYG----DYSKFMKKFMVQKLLGPQALQRSRNIRADE----LERFYKTLLDKAMKKQTVE- 181

  Fly   173 VTWLAQSVLNVLWCLIAGKRIARQEDG---TLRRLL-DLMNRRSKLFDICGGLLAQFPWLRHVAP 233
            :...|..:.|...|.:...|...:|:|   |:|.|: :.:....|.|     |.|.|    |...
plant   182 IRNEAMKLTNNTICKMIMGRSCSEENGEAETVRGLVTESIFLTKKHF-----LGAMF----HKPL 237

  Fly   234 DRTGYNLIQQLNTELYGFFMDTIE----EHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTF 294
            .:.|.:|..:....:...|.:.:|    ||..:|.:...  .||::     :|...:.|.|::.:
plant   238 KKLGISLFAKELMNVSNRFDELLEKILVEHEEKLQEHHQ--TSDML-----DMLLEAYGDENAEY 295

  Fly   295 NET--QLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVA----AASTDAFPH 353
            ..|  |:....:|.|.||::.::|||...:..:...|.:.|:|..::.:.|.    ...|| .|:
plant   296 KITRDQIKSLFVDLFSAGTEASANTIQWTMAEIIKNPKICERLREEIDSVVGKTRLVQETD-LPN 359

  Fly   354 LSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKD 418
            |      .|:.|.:.|..|.....|:.  |......::.|:.||:...:.:::.::..|.:.|:|
plant   360 L------PYLQAIVKEGLRLHPPGPVV--RTFKETCEIKGFYIPEKTRLFVNVYAIMRDPDFWED 416

  Fly   419 PLEFRPERFIDSAGKCFKDE------YFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPA 477
            |.||:||||:.|:....:||      .::|||.|||.|.|..||...:.|.:..:||||..::..
plant   417 PEEFKPERFLASSRLGEEDEKREDMLKYIPFGSGRRACPGSHLAYTVVGSVIGMMVQHFDWIIKG 481

  Fly   478 -------GESPSMVLLPGITLTPKP 495
                   |.:.::.:...:..||.|
plant   482 EKINMKEGGTMTLTMAHPLKCTPVP 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	117/511 (23%)
CYP705A5	NP_199610.1	CYP93	75..504	CDD:410748	104/462 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000