DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP81D1

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_568533.2	Gene:	CYP81D1 / 833619	AraportID:	AT5G36220	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	506	Identity:	120/506 - (23%)
Similarity:	197/506 - (38%)	Gaps:	96/506 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IGFVIYSLIS--------SARRPK--NFPPG-PRFVPWLGNTLQFRKEASAVGGQHILFERWAKD 65
            |..|:||:.|        ...:||  |.||. |.::|.:|: |:..|..         ..|..:.
plant     6 IRVVLYSIFSLIFLIISFKFLKPKKQNLPPSPPGWLPIIGH-LRLLKPP---------IHRTLRS 60

  Fly    66 FRSDL--------VGLKLGREYVVVALGHEMVKEV---QLQEVFEGRPDNFFLRLRTMGTRKGIT 119
            |...|        :.|:||...|.|...|::..|.   :...|...||...      :|...|..
plant    61 FSETLDHNDGGGVMSLRLGSRLVYVVSSHKVAAEECFGKNDVVLANRPQVI------IGKHVGYN 119

  Fly   120 CTD------GQLWYEHRH------FAMKQMRNVGYGRSQMEHHIELEAEELLGQLER---TEEQP 169
            .|:      |..|...|.      |:..::....|.|:.       |...|:.:|.|   |::..
plant   120 NTNMIAAPYGDHWRNLRRLCTIEIFSTHRLNCFLYVRTD-------EVRRLISRLSRLAGTKKTV 177

  Fly   170 IEPVTWLAQSVLNVLWCLIAGKRIARQE---DGTLRRLLDLMNRRSKLFDI-----CGGLLAQFP 226
            :|....|.....|.:..::.|||...:|   :...:|:      |..:.|:     .|..:...|
plant   178 VELKPMLMDLTFNNIMRMMTGKRYYGEETTDEEEAKRV------RKLVADVGANTSSGNAVDYVP 236

  Fly   227 WLRHVAPDRTGY-NLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGE 290
            .||..    :.| |.:::|..|...|....|::.|.|.....:..:..|:   ||:       .:
plant   237 ILRLF----SSYENRVKKLGEETDKFLQGLIDDKRGQQETGTTMIDHLLV---LQK-------SD 287

  Fly   291 SSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLS 355
            ...:.:..:...||...|||:.|::.|:..||..|...|||..|...::...|   ..|.....:
plant   288 IEYYTDQIIKGIILIMVIAGTNTSAVTLEWALSNLLNHPDVISKARDEIDNRV---GLDRLIEEA 349

  Fly   356 RREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPL 420
            ......|:...::|..|....||:..|..|....|:|.||:|:..|:|::..::|.|...|.||.
plant   350 DLSELPYLKNIVLETLRLHPATPLLVPHMASEDCKIGSYDMPRGTTLLVNAWAIHRDPNTWDDPD 414

  Fly   421 EFRPERFIDSAGKCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHF 471
            .|:||||    .|..:.:..:.||:|||.|.|..||:..:...|..::|.|
plant   415 SFKPERF----EKEEEAQKLLAFGLGRRACPGSGLAQRIVGLALGSLIQCF 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	112/478 (23%)
CYP81D1	NP_568533.2	p450	15..489	CDD:386267	116/497 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000