DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP81K2

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_196622.2	Gene:	CYP81K2 / 830925	AraportID:	AT5G10600	Length:	516	Species:	Arabidopsis thaliana

Alignment Length:	539	Identity:	126/539 - (23%)
Similarity:	204/539 - (37%)	Gaps:	99/539 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LIFLCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQH-------ILFER 61
            :|||....:.|.|...:.| :.|| .||.|..:|.:|:.....|........|       :||
plant    23 VIFLLTATLTFFITKFLWS-QNPK-LPPSPTPLPIIGHLHLINKYPLPQALHHLSSNYGPVLF-- 83

  Fly    62 WAKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQE--VFEGRP-----DNFFLRLRTMGTRKGIT 119
                       ||.|...|::....:.::|.....  ....||     |:|....:..|     .
plant    84 -----------LKFGCREVLILSSPDSIEECFTNHDIALANRPKTITSDHFSYGYKNFG-----F 132

  Fly   120 CTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEE---LLGQLERTEEQPIEPVTWLAQSVL 181
            ...|.||...|..:..::    :....::.:..:..||   |...|.|........|....|..|
plant   133 APYGDLWRTLRRLSTLEV----FSSVSLQKNSSIRTEEVSNLCSSLFRFSGGNSCKVDLRYQFTL 193

  Fly   182 ---NVLWCLIAGKRIARQEDG-TLRRLLDLMNRR--SKL--FDICGGLLAQFPWLRHVAPDRTGY 238
               :|:..|::|.|...:.|. :..:.||....|  |.|  .::|.    .||.||.:     ||
plant   194 LTAHVMLRLVSGNRGVNESDSESETKFLDEFKSRFFSSLSSMNVCD----YFPVLRWI-----GY 249

  Fly   239 N-------LIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNE 296
            .       .||::..|.....:|.|     ::.|..|.......:..|||       .|...:::
plant   250 KGLENRVIEIQRMRDEYLQRLIDDI-----RMKKFDSTGSVVEKFLKLQE-------SEPEFYSD 302

  Fly   297 TQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFD 361
            ..:...::..|.|||.|:..|:..|:.:|...||..:|:..::.::|..........||   :..
plant   303 DVIKGIVVLMFNAGSDTSPVTMEWAMALLLNHPDKLDKVREEIKSNVKHKGIIQDSDLS---SLP 364

  Fly   362 YMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPER 426
            |:...|.|..|.....||..|..:.....||.|:||:|..:|::..:||.|.|.|::...|:|||
plant   365 YLRCVIYETLRLHPAAPILPPHCSSKRFNLGNYEIPENTVLLVNAWAVHRDGELWEEADVFKPER 429

  Fly   427 FIDSAGKCFKDEY-FMPFGMGRRRCLGDALARACIFSFLVRIVQ----------------HFSVV 474
            |.:..|.  :|.: |:|||:|||.|....||...:...:..:||                .|||.
plant   430 FEEFVGD--RDGFRFLPFGVGRRACPAAGLAMRVVSLAVGALVQCFEWEKVEKEDIDMRPAFSVA 492

  Fly   475 LPAGESPSMVLLPGITLTP 493
            :...|....:|.|...:.|
plant   493 MDRAEPLIALLKPCPEMVP 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	118/513 (23%)
CYP81K2	NP_196622.2	p450	18..511	CDD:299894	125/537 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000