DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP93D1

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_196307.1	Gene:	CYP93D1 / 830580	AraportID:	AT5G06900	Length:	507	Species:	Arabidopsis thaliana

Alignment Length:	504	Identity:	113/504 - (22%)
Similarity:	210/504 - (41%)	Gaps:	54/504 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SALIFLCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDF 66
            |.:|.:| :.|..:|.::.:..|.....||.|..:|.:|:.......|..  ..|.|..|:
plant     8 SVIILVC-LGITVLIQAITNRLRDRLPLPPSPTALPIIGHIHLLGPIAHQ--ALHKLSIRY---- 65

  Fly    67 RSDLVGLKLGREYVVVALGHEMVKEV-QLQEV-FEGRPDNFFLRLRTMGTRKGITCTDGQLWYEH 129
             ..|:.|.:|....::....||..|: :..|: |..||....:...|.|:....:...|..|...
plant    66 -GPLMYLFIGSIPNLIVSSAEMANEILKSNELNFLNRPTMQNVDYLTYGSADFFSAPYGLHWKFM 129

  Fly   130 RHFAMKQMRNVGYGRSQMEHHIELEAEE----LLGQLERTE-EQPIEPVTWLAQSVLNVLWCLIA 189
            :...|.::    :....::..:.:.:||    |:..|::.| |:.:.....|.:...|::..::.
plant   130 KRICMVEL----FSSRALDSFVSVRSEELKKLLIRVLKKAEAEESVNLGEQLKELTSNIITRMMF 190

  Fly   190 GKRIARQEDG-----TLRRLLDLMNRRSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLNTELY 249
            .|..:..:.|     .::.:::| |..:..|::.    ..|.:|:.:  |..|.....:...:.|
plant   191 RKMQSDSDGGEKSEEVIKMVVEL-NELAGFFNVS----ETFWFLKRL--DLQGLKKRLKNARDKY 248

  Fly   250 GFFMDTI-EEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVMTILDFFIAGSQT 313
            ...::.| |||  :.:|..:..|.:::...|...:|::|..:.:..|....:|.|   :..|:.|
plant   249 DVIIERIMEEH--ESSKKNATGERNMLDVLLDIYEDKNAEMKLTRENIKAFIMNI---YGGGTDT 308

  Fly   314 TSNTINLALMVLAMRPDVQEKL---FSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFH 375
            ::.|:..||..|...|::.:|.   ..||..:..........:||      |..|.:.|..|...
plant   309 SAITVEWALAELINHPEIMKKAQQEIEQVVGNKRVVEESDLCNLS------YTQAVVKETMRLHP 367

  Fly   376 ITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKDEYF 440
            ..||. .|.:.....:.|:.||....:::::.::..|...|:||||||||||..|..|.. .|..
plant   368 GGPIF-VRESDEECAVAGFRIPAKTRVIVNVWAIGRDSNQWEDPLEFRPERFEGSEWKVM-SEKM 430

  Fly   441 MPFGMGRRRCLGDALARACIFSFLVRIVQHF------SVVLPAGESPSM 483
            |.||.|||.|.|:.:....:...|..|:|.|      ||.:..|...|:
plant   431 MSFGAGRRSCPGEKMVFRFVPIILAAIIQCFELKVKGSVDMDEGTGSSL 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	107/476 (22%)
CYP93D1	NP_196307.1	p450	7..500	CDD:299894	113/504 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000