DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP79A2

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_568153.2	Gene:	CYP79A2 / 830408	AraportID:	AT5G05260	Length:	529	Species:	Arabidopsis thaliana

Alignment Length:	526	Identity:	121/526 - (23%)
Similarity:	207/526 - (39%)	Gaps:	103/526 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LCAILIGFVIYSL-----------ISSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFE 60
            :.|.:||.::.:|           :.|..|..:.||||:..|.:||..:.      :|....:|
plant     7 MLAFIIGLLLLALTMKRKEKKKTMLISPTRNLSLPPGPKSWPLIGNLPEI------LGRNKPVF- 64

  Fly    61 RW----AKDFRSDLVGLKLGREYVVVALGHEMVKEV--QLQEVFEGRPDNFFLRLRTMGTRKGIT 119
            ||    .|:..:|:..::|...:|:......:.:|:  :...||..||       .||||.   .
plant    65 RWIHSLMKELNTDIACIRLANTHVIPVTSPRIAREILKKQDSVFATRP-------LTMGTE---Y 119

  Fly   120 CTDGQLW--YEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWL-AQSVL 181
            |:.|.|.  .|.:....|:||.|      :..|:..:....:...:||||.. ..|.:: .:||.
plant   120 CSRGYLTVAVEPQGEQWKKMRRV------VASHVTSKKSFQMMLQKRTEEAD-NLVRYINNRSVK 177

  Fly   182 N------VLWCLIAGKR----IARQ------------EDGTLRRLLDLMNRRSKLFDICGGLLA- 223
            |      |:...:|.::    :||:            |||:...|.::.:..| ||.:...|.|
plant   178 NRGNAFVVIDLRLAVRQYSGNVARKMMFGIRHFGKGSEDGSGPGLEEIEHVES-LFTVLTHLYAF 241

  Fly   224 ----QFPWLRHVAPDRTGYNLI---QQLNTELYG--FFMDTIEEHRRQLAKDPSPAESDLIYAYL 279
                ..||||.:  |..|:..:   ...|...|.  |..:.:.:.|....|:|.......|.|
plant   242 ALSDYVPWLRFL--DLEGHEKVVSNAMRNVSKYNDPFVDERLMQWRNGKMKEPQDFLDMFIIA-- 302

  Fly   280 QEMKDRSAGGESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVA 344
               ||...   ..|.::.::...:.:..:|.....||.....:..:...|.:.:|...::...|.
plant   303 ---KDTDG---KPTLSDEEIKAQVTELMLATVDNPSNAAEWGMAEMINEPSIMQKAVEEIDRVVG 361

  Fly   345 ----AASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILIS 405
                ...:| .|:|      :|:.|.:.|..|...:.|...|..:...|.:.||.|||.:.:|||
plant   362 KDRLVIESD-LPNL------NYVKACVKEAFRLHPVAPFNLPHMSTTDTVVDGYFIPKGSHVLIS 419

  Fly   406 LRSVHLDKEHWKDPLEFRPERFIDSAGKCF----KDEYFMPFGMGRRRCLGDALARACIFSFLVR 466
            ...:..:...|..|.:|.|||.: |...|.    .|...:.|..|||.|:|..:..|..:..|.|
plant   420 RMGIGRNPSVWDKPHKFDPERHL-STNTCVDLNESDLNIISFSAGRRGCMGVDIGSAMTYMLLAR 483

  Fly   467 IVQHFS 472
            ::|.|:
plant   484 LIQGFT 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	115/492 (23%)
CYP79A2	NP_568153.2	CYP79	76..522	CDD:410751	103/450 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000