DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP81D5

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_195449.1	Gene:	CYP81D5 / 829887	AraportID:	AT4G37320	Length:	495	Species:	Arabidopsis thaliana

Alignment Length:	518	Identity:	119/518 - (22%)
Similarity:	202/518 - (38%)	Gaps:	67/518 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSALIFLCAILIGFVIYSLISSARRPKNFPPGPRF-VPWLGNTLQFRKEASAVGGQHILFERWAK 64
            ::.::.|..:.:...|..|::.:.|..|.||.|.: :|.:|: |...|:.     .|..|...:|
plant     3 LTQILLLSFLFLTISIKLLLTKSNRKPNLPPSPAYPLPVIGH-LHLLKQP-----VHRTFHSISK 61

  Fly    65 DF-RSDLVGLKLGREYVVVALGHEMVKE--VQLQEVFEGRPDNFFLRLRTMGTRKGITCTDGQLW 126
            .. .:.:..|:||...|.|...|.:.:|  .:...|...|||....:.........|..:.|..|
plant    62 SLGNAPIFHLRLGNRLVYVISSHSIAEECFTKNDVVLANRPDIIMAKHVGYNFTNMIAASYGDHW 126

  Fly   127 YEHRHFAMKQMRNVGYGRSQMEHHIEL-------EAEELLGQLERTEEQ---PIEPVTWLAQSVL 181
            ...|..|..::.:        .|.|..       |...|:..|.|....   .:|..:.|.....
plant   127 RNLRRIAAVEIFS--------SHRISTFSSIRKDEIRRLITHLSRDSLHGFVEVELKSLLTNLAF 183

  Fly   182 NVLWCLIAGKRI--ARQEDGTLRRLLDLMNRRSKLFDICGG--------LLAQFPWLRHVAPDRT 236
            |.:..::||||.  ...||....:|:     |..:.:|..|        .|....|:.:..
plant   184 NNIIMMVAGKRYYGTGTEDNDEAKLV-----RELIAEIMAGAGSGNLADYLPSINWVTNFE---- 239

  Fly   237 GYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVM 301
              |..:.|...|.......::|.|.:..|..:..:..|.:   ||.       |...:.:..:..
plant   240 --NQTKILGNRLDRVLQKLVDEKRAEKEKGQTLIDHLLSF---QET-------EPEYYTDVIIKG 292

  Fly   302 TILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAF 366
            .||...:||:.|:|.|:..|:..|...|::.||..:::...:   .:|.....|......|:...
plant   293 IILALVLAGTDTSSVTLEWAMSNLLNHPEILEKARAEIDDKI---GSDRLVEESDIVNLHYLQNI 354

  Fly   367 IMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSA 431
            :.|..|.:...|:..|..:....|:.|||:|:...:|.::.::|.|...|::|..|:|||| :..
plant   355 VSETLRLYPAVPLLLPHFSSDECKVAGYDMPRRTLLLTNVWAMHRDPGLWEEPERFKPERF-EKE 418

  Fly   432 GKCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGESPSMVLLPGITLTPK 494
            |:..|   .||||||||.|.|..|.:..:...|..::|.|.......|...|....|||: ||
plant   419 GEARK---LMPFGMGRRACPGAELGKRLVSLALGCLIQSFEWERVGAELVDMTEGEGITM-PK 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	114/489 (23%)
CYP81D5	NP_195449.1	p450	1..488	CDD:386267	119/518 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000