DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP705A2

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_193270.1	Gene:	CYP705A2 / 827201	AraportID:	AT4G15350	Length:	509	Species:	Arabidopsis thaliana

Alignment Length:	545	Identity:	130/545 - (23%)
Similarity:	228/545 - (41%)	Gaps:	90/545 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LIFLCAILIGFVIYSLI----SSARRPKNFPPGPRFVPWLG-------NTLQFRKEASAVGGQHI 57
            :||:...|:.|:.|||.    ..:|..::.||.|..:|.:|       :||           .|.
plant     5 IIFILLCLLSFLCYSLFFMKPKDSRDGRDLPPSPPSLPIIGHLHLILLSTL-----------THK 58

  Fly    58 LFERWAKDFRSDLVGLKLGREYVVVA----LGHEMVKEVQLQEVFEGRP---DNFFLRLRTMGTR 115
            .|:|.:..: ..|:.|::....:|:|    :.:|:.::..:...|...|   ::.||     |:.
plant    59 SFQRLSSKY-GPLLHLRIFHVPIVLASSASVAYEIFRDQDVNVSFRHSPPIEESLFL-----GSY 117

  Fly   116 KGITCTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERT------EEQPIEPVT 174
            ..|:...|..|    .|..|.|.....|...:|.......:| |.:..:|      :::.:|.|.
plant   118 SFISAPYGDYW----KFMRKLMVTKILGPQALERSRRFREDE-LDRFYKTLLDKAMKKESVEIVE 177

  Fly   175 WLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDL----MNRRSKLFDICGGLLAQFPWLRHVAPDR 235
            ..|:...|.:..:|.| |...:|.|...|:..|    |....|:|      ||.   :.|....:
plant   178 EAAKLNNNTICKMIMG-RSCSEETGEAERIRGLVTESMALTKKIF------LAT---IFHKPLKK 232

  Fly   236 TGYNLIQQLNTELYGFFMDTIE----EHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNE 296
            .|.:|.::....:...|.:.:|    ||..::  :.....:|::...|:..:|.:|   ......
plant   233 LGISLFKKEIMSVSRKFDELLEKILVEHEEKM--EEHHQGTDMMDVLLEAYRDENA---EYKITR 292

  Fly   297 TQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAA----STDAFPHLSRR 357
            ..:....:|.||||:.|:|.||...:..:...|.:.|:|..::...|...    .|| .|:|.
plant   293 NHIKSMFVDLFIAGTDTSSTTIQWIMAEIINHPKILERLREEIDFVVGKTRLIQETD-LPNLL-- 354

  Fly   358 EAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEF 422
                |:.|.|.|..|.....|:. ||......::.|:.||:...::::..::..|.:.|:||.||
plant   355 ----YLQAIIKEGLRLHPPGPLL-PRTVQERCEIKGFHIPEKTILVVNSYAIMRDPDFWEDPDEF 414

  Fly   423 RPERFIDSAGKCFKDEY------FMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGESP 481
            :||||:..:....:||.      ::||..|||.|.|..||.|.:.:.:..:||.|...: .||:.
plant   415 KPERFLSISRSGQEDEIRDKFLKYIPFASGRRGCPGTNLAYASVGTAVGVMVQCFDWKI-EGENV 478

  Fly   482 SMVLLPG-ITLT-PKPYKVQFVKRT 504
            :|....| :.|| ..|.|...|.||
plant   479 NMNEAAGTMVLTMAHPLKCTPVPRT 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	119/509 (23%)
CYP705A2	NP_193270.1	p450	52..508	CDD:386267	117/498 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000