DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP706A5

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_192968.3	Gene:	CYP706A5 / 826840	AraportID:	AT4G12310	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	523	Identity:	135/523 - (25%)
Similarity:	225/523 - (43%)	Gaps:	78/523 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 AILIGFVIYSLI-----SSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRS 68
            |:||....:|::     .|.:.|  .|||||.:|.:|| |.|...     ..|..|.:.|:. ..
plant    21 AVLILTATFSILWYIFKRSPQPP--LPPGPRGLPIVGN-LPFLDP-----DLHTYFTKLAQS-HG 76

  Fly    69 DLVGLKLGREYVVV----ALGHEMVKEVQLQEVFEGRPDNFFLRLRTMGTRKGITCTDGQLWYEH 129
            .:..|.||.:..||    :|..|::|:..:.  |.........|..|.|....:....|..|...
plant    77 PIFKLNLGSKLTVVVNSPSLASEILKDQDIN--FSNHDVPLTARAVTYGGLDLVWLPYGAEWRML 139

  Fly   130 RHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERT--------EEQPIEPVTWLAQSVLNVLWC 186
            |.....::    :.|..::...||..:|:   .|||        |:.|:.....|..:::|::..
plant   140 RKVCAAKL----FSRKTLDSFYELRRKEI---RERTRCLYQKGLEKSPVNVGEQLFLTMMNLMMN 197

  Fly   187 LIAGKRIARQED----GT--------LRRLLDLMNRRSKLFDICGGLLAQFPWLRHVAPDRTGYN 239
            ::.|..: :.||    ||        :.|||.:.| .|..|.    :||:|        |..|
plant   198 MLWGGSV-KAEDMESVGTEFKGVISEITRLLGVPN-VSDFFP----MLARF--------DLQG-- 246

  Fly   240 LIQQLNTELYGFFMD-----TIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGE-SSTFNETQ 298
            |:::::  ||...:|     .||:.:|..::|....|......:|.:::|:.|..: ..|.|..:
plant   247 LVKKMH--LYARDLDAILDRAIEQMQRLRSRDGDDGECKDFLQHLMKLRDQEADSDVPITMNHVK 309

  Fly   299 LVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYM 363
            .|  ::|..:.|:::::|||...:..|...|::..:...::...|...:.....|::   :..|:
plant   310 AV--LMDMVVGGTESSTNTIEFVMAELISNPELMRRAQQELDEVVGKDNIVEESHIT---SLPYI 369

  Fly   364 DAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFI 428
            .|.:.|..|.:...|:..|.|......:|||.||||..|.|::.|:..|...|:.|.|||||||:
plant   370 LAVLKETLRLYPTIPLLVPHRPSETALVGGYTIPKNTKIFINVWSIQRDPNVWEYPTEFRPERFL 434

  Fly   429 DSAGKCF--KDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGESPSMVLLPGITL 491
            |.....|  .|..::|||.|||.|.|.|||...|...|..::..|...:|.|....:....||.|
plant   435 DKKSCDFTGTDYSYLPFGSGRRICAGIALAERMILYTLATLLHSFDWTIPDGHVLDLEEKFGIVL 499

  Fly   492 TPK 494
            ..|
plant   500 KLK 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	129/497 (26%)
CYP706A5	NP_192968.3	p450	53..518	CDD:299894	123/489 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000